10 件のレコードが見つかりました。
Roles of Supersaturation and Liquid–Liquid Phase Separation for Enhanced Oral Absorption of Poorly Soluble Drugs from Amorphous Solid Dispersions
- 論文
- 著者
-
Kohsaku Kawakami
- キーワード
- Amorphous solid dispersion, Crystallizaion, Supersaturation, Liquid–liquid phase separation, Membrane permeability, Oral absorption
- 刊行年月日
- 更新時刻
- 2025-04-30 11:12:54 +0900
Long-term physical stability of amorphous solid dispersions: Comparison of detection powers of common evaluation methods for spray-dried and hot-melt extruded formulations
- 論文
- 著者
-
Kohsaku Kawakami
;
Taichi Ishitsuka
;
Masafumi Fukiage
;
Yohei Nishida
;
Tetsuo Shirai
;
Yosuke Hirai
;
Tetsu Hideshima
;
Fumiaki Tanabe
;
Koji Shinoda
;
Ryota Tamate
;
Takuya Fujita
- キーワード
- Amorphous solid dispersion, Crystallization, Stability, Dissolution study
- 刊行年月日
- 2024-06-29
- 更新時刻
- 2025-06-05 17:10:10 +0900
Immunostimulatory Effects of Guanine-Quadruplex Topologies as Scaffolds for CpG Oligodeoxynucleotides
- 論文
- 著者
-
Soumitra Pathak
;
Nguyen Bui Thao Le
;
Taiji Oyama
;
Yusuke Odahara
;
Atsuya Momotake
;
Kazunori Ikebukuro
;
Chiho Kataoka-Hamai
;
Chiaki Yoshikawa
;
Kohsaku Kawakami
;
Yoshihisa Kaizuka
;
Tomohiko Yamazaki
- キーワード
- CpG oligodeoxynucleotides, adjuvants, guanine-quadruplex, immune response, serum stability, toll like receptor 9, topology
- 刊行年月日
- 更新時刻
- 2025-03-27 11:03:34 +0900
Lateral nanoarchitectonics from nano to life: ongoing challenges in interfacial chemical science
- 論文
- 著者
-
Jingwen Song
;
Anna Jancik-Prochazkova
;
Kohsaku Kawakami
;
Katsuhiko Ariga
- キーワード
- nanoarchitectonics, interface, Langmuir–Blodgett film, layer-by-layer assembly, biological membrane
- 刊行年月日
- 2024-10-28
- 更新時刻
- 2024-11-21 16:31:11 +0900
Toward the Establishment of a Harmonized Physicochemical Profiling Platform for Therapeutic Oligonucleotides: A Case Study for Aptamers Where the Higher-Order Structure Influences Physical Properties
- 論文
- 著者
-
Shoko Takeuchi
;
Tomohiko Yamazaki
;
Katsutoshi Yamaguchi
;
Fusae Komura
;
Takahiro Tabata
;
Hirotaka Nishi
;
Satomi Azumai
;
Kanako Miura
;
Mai Hirokawa
;
Keisuke Ikemoto
;
Kohsaku Kawakami
- キーワード
- oligonucleotide, higher-order structure, thrombin aptamer, G-quadruplex, physicochemical profiling
- 刊行年月日
- 2024-07-01
- 更新時刻
- 2024-10-08 13:22:18 +0900
Influence of Nucleation on Relaxation, Molecular Cooperativity, and Physical Stability of Celecoxib Glass
- 論文
- 著者
-
Xue Han
;
Kexin Dai
;
Kohsaku Kawakami
- キーワード
- Glass, Nucleation, Crystallization, Relaxation, Cooperative rearranging region
- 刊行年月日
- 2024-04-01
- 更新時刻
- 2025-02-24 12:30:14 +0900
Bio-gel nanoarchitectonics in tissue engineering
- 論文
- 著者
-
Jingwen Song
;
Wenyan Lyu
;
Kohsaku Kawakami
;
Katsuhiko Ariga
- キーワード
- nanoarchitectonics, Bio-gel, tissue engineering
- 刊行年月日
- 2024-06-13
- 更新時刻
- 2024-07-19 12:30:33 +0900
Molecular machines working at interfaces: physics, chemistry, evolution and nanoarchitectonics
- 論文
- 著者
-
Katsuhiko Ariga
;
Jingwen Song
;
Kohsaku Kawakami
- キーワード
- Molecular machine, interface, nanoarchitectonics
- 刊行年月日
- 2024-04-09
- 更新時刻
- 2024-05-09 16:30:20 +0900
Influence of the Charge Ratio of Guanine-Quadruplex Structure-Based CpG Oligodeoxynucleotides and Cationic DOTAP Liposomes on Cytokine Induction Profiles
- 論文
- 著者
-
Nguyen Bui Thao Le
;
Anh Thi Tram Tu
;
Dandan Zhao
;
Chiaki Yoshikawa
;
Kohsaku Kawakami
;
Yoshihisa Kaizuka
;
Tomohiko Yamazaki
- キーワード
- guanine quadruplex, CpG oligodeoxynucleotides, cationic liposomes, vaccine, immunotherapy, DNA delivery, liposome
- 刊行年月日
- 更新時刻
- 2024-04-30 12:30:21 +0900
Layer-by-layer designer nanoarchitectonics for physical and chemical communications in functional materials
- 論文
- 著者
-
Katsuhiko Ariga
;
Jingwen Song
;
Kohsaku Kawakami
- キーワード
- Nanoarchitectonics, Layer-by-layer assembly, Thin films, Interface, Communications, Functional materials
- 刊行年月日
- 2024-01-18
- 更新時刻
- 2024-02-26 12:30:14 +0900