20 records found.
Protein nanoarchitectonics at liquid-related interfaces: physicochemical communications with biological processes
- Journal article
- Creator
-
Katsuhiko Ariga (author) (Search by this author)
;
Jingwen Song (author) (Search by this author)
;
Kohsaku Kawakami (author) (Search by this author)
- Keyword
- Protein, nanoarchitectonics, interface, liquid
- Date published
- 2026-01-19
- Updated at
- 2026-02-27 16:31:06 +0900
Nucleation in Amorphous Terfenadine at a Temperature Much Lower than the Glass Transition Temperature and Its Impact on Physical Stability
- Journal article
- Creator
-
;Katsutoshi Yamaguchi (author) (Search by this author);Yuya Ishizuka (author) (Search by this author);Etsushi Yoshikawa (author) (Search by this author);Takashi Makishima (author) (Search by this author);Ryo Mizoguchi (author) (Search by this author)Kohsaku Kawakami (author) (Search by this author)National Institute for Materials Science
- Keyword
- amorphous, nucleation, crystal growth, physical stability, local molecular mobility
- Date published
- 2025-10-06
- Updated at
- 2025-11-25 12:30:07 +0900
Impact of Lipid Bilayer Composition and Physicochemical Properties on Constitution of a Transmembrane Helical Peptide into Exosome-Mimetic Vesicles
- Journal article
- Creator
-
Shiho Tsutsumi (author) (Search by this author)
https://orcid.org/0009-0006-8089-6477
(unauthenticated)
;
Yuki Takechi-Haraya (author) (Search by this author)
https://orcid.org/0000-0002-8754-6457
(unauthenticated)
;
Yasuhiro Abe (author) (Search by this author)
https://orcid.org/0000-0002-5931-6590
(unauthenticated)
;
Kohsaku Kawakami (author) (Search by this author)
- Keyword
- Exosomes, Exosome mimetic vesicles, lipid membrane, helical peptide
- Date published
- 2025-11-03
- Updated at
- 2025-11-25 12:30:04 +0900
Leveraging Molecular Interactions to Develop a Generalized Design Framework for Coamorphous Drug–Drug Mixtures Exhibiting Elevated Glass Transition Temperatures
- Journal article
- Creator
-
;Dani Lakshman Yarlagadda (author) (Search by this author)Kohsaku Kawakami (author) (Search by this author)National Institute for Materials Science
;
Satyavrata Samavedi (author) (Search by this author)
https://orcid.org/0000-0003-1196-1598
(unauthenticated)
- Keyword
- Molecular cooperativity, Co-amorphous mixture, Glass transition temperature, Gordon-Taylor equation, Molecular interaction, Amorphous drug stability
- Date published
- 2025-06-02
- Updated at
- 2026-04-30 12:01:11 +0900
Influence of Pore Size of Mesoporous Silica on Physical Stability of Overloaded Celecoxib Glass
- Journal article
- Creator
-
Xue Han (author) (Search by this author)National Institute for Materials Science
;
Kohsaku Kawakami (author) (Search by this author)National Institute for Materials Science
- Keyword
- glass, mesoporous silica, crystallization, cooperatively rearranging region, broadband dielectric spectroscopy, differential scanning calorimetry
- Date published
- 2025-05-05
- Updated at
- 2025-11-10 12:30:15 +0900
From Inception to Innovation: 20 Years of Nanoarchitectonics
- Journal article
- Creator
-
Katsuhiko Ariga (author) (Search by this author)
;
Jingwen Song (author) (Search by this author)
;
Kohsaku Kawakami (author) (Search by this author)
- Keyword
- Interface, Layer-by-layer, Liquid interface, Manipulation, Nanoarchitectonics
- Date published
- 2025-08-31
- Updated at
- 2025-10-21 15:50:02 +0900
Crystal Nucleation in Ibuprofen Glass: Possible Relevance between the Characteristic Length of the Cooperatively Rearranging Region and the Size of Crystal Nuclei
- Journal article
- Creator
-
Kohsaku Kawakami (author) (Search by this author)
;
Kaoru Ohyama (author) (Search by this author)
- Keyword
- Pharmaceutical glass, Nucleation, Crystallization, Cooperatively rearranging region
- Date published
- 2025-02-20
- Updated at
- 2025-11-25 12:30:10 +0900
Roles of Supersaturation and Liquid–Liquid Phase Separation for Enhanced Oral Absorption of Poorly Soluble Drugs from Amorphous Solid Dispersions
- Journal article
- Creator
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Kohsaku Kawakami (author) (Search by this author)
- Keyword
- Amorphous solid dispersion, Crystallizaion, Supersaturation, Liquid–liquid phase separation, Membrane permeability, Oral absorption
- Date published
- 2025-02-16
- Updated at
- 2025-04-30 12:30:20 +0900
Bridging the gap between in vitro and in vivo solubility-permeability interplay
- Journal article
- Creator
-
;Michinori Oikawa (author) (Search by this author);Satoru Matsuura (author) (Search by this author);Takeyuki Okudaira (author) (Search by this author);Ryo Ito (author) (Search by this author);Kanako Arima (author) (Search by this author);Masahiro Fushimi (author) (Search by this author);Takamasa Oda (author) (Search by this author);Kaoru Ohyama (author) (Search by this author)Kohsaku Kawakami (author) (Search by this author)
- Keyword
- Solubility-permeability interplay, Solubilization, Poorly soluble drug, Oral absorption, Cyclodextrin
- Date published
- 2024-10-22
- Updated at
- 2025-10-23 08:30:07 +0900
Long-term physical stability of amorphous solid dispersions: Comparison of detection powers of common evaluation methods for spray-dried and hot-melt extruded formulations
- Journal article
- Creator
-
Kohsaku Kawakami (author) (Search by this author)
;
;Taichi Ishitsuka (author) (Search by this author);Masafumi Fukiage (author) (Search by this author);Yohei Nishida (author) (Search by this author);Tetsuo Shirai (author) (Search by this author);Yosuke Hirai (author) (Search by this author);Tetsu Hideshima (author) (Search by this author);Fumiaki Tanabe (author) (Search by this author);Koji Shinoda (author) (Search by this author)Ryota Tamate (author) (Search by this author)
;
Takuya Fujita (author) (Search by this author)
- Keyword
- Amorphous solid dispersion, Crystallization, Stability, Dissolution study
- Date published
- 2024-06-29
- Updated at
- 2025-06-29 08:30:20 +0900