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Development of novel bone‐like nanocomposite coating of hydroxyapatite/collagen on titanium by modified electrophoretic deposition

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　This study demonstrated the application of a modified EPD technique utilizing Mg2+ ions to coat a bone-like hydroxyapatite/collagen nanocomposite on a titanium substrate. The coating thickness was successfully controlled by varying the applied voltage and/or the treatment time. The adhesive strength of the modified EPD coating, evaluated by the tape test, showed class 0 and drastically increased in comparison to that of the conventional EPD coating, class 5 . The MG63 cells on the HAp/Col-coated Ti demonstrated similar proliferation to and superior alkaline phosphatase activity to that on the bare Ti. The results of the study indicated the HAp/Col-coated Ti prepared by the modified EPD is effective for applications in novel instruments such as subperiosteal temporary anchorage devices.

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  • 31/03/2021
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  • This is the peer reviewed version of the following article: Journal of Biomedical Materials Research Part A, which has been published in final form at https://doi.org/10.1002/jbm.a.37182. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
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  • Accepted manuscript
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  • Funder identifier
    19im0210221h0001
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    Japan Agency for Medical Research and Development

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