2 records found.
Toward the Establishment of a Harmonized Physicochemical Profiling Platform for Therapeutic Oligonucleotides: A Case Study for Aptamers Where the Higher-Order Structure Influences Physical Properties
- Article
- Creator
-
Shoko Takeuchi
;
Tomohiko Yamazaki
;
Katsutoshi Yamaguchi
;
Fusae Komura
;
Takahiro Tabata
;
Hirotaka Nishi
;
Satomi Azumai
;
Kanako Miura
;
Mai Hirokawa
;
Keisuke Ikemoto
;
Kohsaku Kawakami
- Keyword
- oligonucleotide, higher-order structure, thrombin aptamer, G-quadruplex, physicochemical profiling
- Date published
- 2024-07-01
- Updated at
- 2025-06-15 08:30:25 +0900
G-Quadruplex Structure Improves the Immunostimulatory Effects of CpG Oligonucleotides
- Article
- Creator
-
Hoshi, Kazuaki
;
Yamazaki, Tomohiko
;
Sugiyama, Yuuki
;
Tsukakoshi, Kaori
;
Tsugawa, Wakako
;
Sode, Koji
;
Ikebukuro, Kazunori
- Keyword
- IL-6, toll-like receptor 9, CpG ODN, G-quadruplex, peripheral blood mononuclear cells
- Date published
- 2019-03-05
- Updated at
- 2024-01-05 22:13:10 +0900