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Description:

Actinodaphne angustifolia (Lauraceae), traditionally used for treating inflammatory and allergic disorders, was investigated for its anti-allergic potential using integrated in vivo and in silico approaches. Safety evaluation in accordance with OECD guidelines confirmed the non-toxic nature of the ethanolic leaf extract. In a toluene 2,4-diisocyanate-induced allergic model, the extract reduced allergic symptoms, including sneezing, nasal scratching, and nasal scores, also normalizing elevated white blood cell counts in blood and bronchoalveolar lavage fluid.

Rights:

• Creative Commons BY-NC Attribution-NonCommercial 4.0 International
  

Keyword: Actinodaphne angustifolia, allergy, in silico molecular docking, phytoconstituents

Date published: 2026-09-22

Publisher: Wiley

Journal:

• Chemistry & Biodiversity (ISSN: 16121872) vol. 23 issue. 9 e71727

Funding:

• Khulna University KU/GACELL04(8)/2000‐295

Manuscript type: Publisher's version (Version of record)

MDR DOI:

First published URL: https://doi.org/10.1002/cbdv.71727

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Updated at: 2026-09-24 11:37:19 +0900

Published on MDR: 2026-09-24 16:45:08 +0900