Article Development of Layer-by-Layer Magnetic Nanoparticles for Application to Radiotherapy of Pancreatic Cancer

Nobuyoshi Fukumitsu ; Yoshitaka Matsumoto ; Lili Chen (National Institute for Materials Science) ; Yu Sugawara ; Nanami Fujisawa SAMURAI ORCID (National Institute for Materials Science) ; Eri Niiyama ; Sosuke Ouchi (National Institute for Materials Science) ; Emiho Oe (National Institute for Materials Science) ; Takashi Saito ; Mitsuhiro Ebara SAMURAI ORCID (National Institute for Materials Science)

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Citation
Nobuyoshi Fukumitsu, Yoshitaka Matsumoto, Lili Chen, Yu Sugawara, Nanami Fujisawa, Eri Niiyama, Sosuke Ouchi, Emiho Oe, Takashi Saito, Mitsuhiro Ebara. Development of Layer-by-Layer Magnetic Nanoparticles for Application to Radiotherapy of Pancreatic Cancer. Molecules. 2025, 30 (6), 1382. https://doi.org/10.3390/molecules30061382

Description:

(abstract)

This study introduces a novel drug delivery system using gemcitabine (GEM)-loaded layer-by-layer magnetic nanoparticles (LBL MNPs) combined with alternating magnetic field (AMF) application and X-ray irradiation to enhance therapeutic efficacy.

Rights:

Keyword: Layer by layer, Magnetic nanoparticle, Radiotherapy

Date published: 2025-03-20

Publisher: MDPI AG

Journal:

  • Molecules (ISSN: 14203049) vol. 30 issue. 6 1382

Funding:

  • JSPS KAKENHI JP15K19768
  • JSPS KAKENHI JP17K15016
  • JSPS KAKENHI TK20-044
  • Tsukuba Innovation Arena (TIA) Collaborative Program Exploration and Promotion Project Kakehashi JP15K19768
  • Tsukuba Innovation Arena (TIA) Collaborative Program Exploration and Promotion Project Kakehashi JP17K15016
  • Tsukuba Innovation Arena (TIA) Collaborative Program Exploration and Promotion Project Kakehashi TK20-044

Manuscript type: Publisher's version (Version of record)

MDR DOI:

First published URL: https://doi.org/10.3390/molecules30061382

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Updated at: 2026-01-06 15:51:34 +0900

Published on MDR: 2026-01-07 08:24:33 +0900

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