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説明:

The heating performance of magnetic nanoparticles for hyperthermia is typically assessed by the specific absorption rate (SARnano), measured under laboratory-specific irradiation conditions. However, since SARnano depends heavily on magnetic field amplitude and frequency, comparing material performance across studies is challenging. This study introduces additional indicators, such as the heating selectivity ratio (which reflects side effects) and the specific power factor (device load), and demonstrates that the ratio of experimentally generated heat to theoretical maximum heat output is a more reliable metric for heat generation efficiency, independent of irradiation conditions. Conventional measurement conditions may not reveal nanoparticles with the highest heating potential, so a predictive method based on blocking temperature and switching field distribution was developed. This method accurately predicts heating behavior for immobilized nanoparticles but needs improvement to account for dipolar interactions and particle rotations. The proposed metrics and framework provide a more robust approach to evaluating nanoparticle performance for hyperthermia.

権利情報:

• Creative Commons BY Attribution 4.0 International
  

キーワード: Hyperthermia treatment, Magnetic nanoparticle, Magnetic heating efficiency, Specific absorption rate, Blocking temperature, Switching field distribution

刊行年月日: 2026-06-17

出版者: Elsevier BV

掲載誌:

• Materials Today Nano (ISSN: 25888420) vol. 35 100869

研究助成金:

• Government of Japan Ministry of Education Culture Sports Science and Technology
• Japan Society for the Promotion of Science

原稿種別: 出版者版 (Version of record)

MDR DOI:

公開URL: https://doi.org/10.1016/j.mtnano.2026.100869

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更新時刻: 2026-06-26 10:43:39 +0900

MDRでの公開時刻: 2026-06-26 14:28:24 +0900