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説明:

To avoid the toxic effect of released nickel ions and compounds from conventional stainless steels, nickel-free austenitic stainless steels have been developed. We previously established a new manufacturing process to produce nickel-free austenitic stainless steel that involves nitrogen adsorption treatment. Although the cytocompatibility of nickel-free austenitic stainless steel produced using this method has been evaluated using two viability assay, molecular level analysis, such as gene expression analysis, has not been previously performed. In the present study, the cytotoxicity of our nickel-free austenitic stainless steel, as well as of commercially available metal materials, was evaluated by analysis of heat shock protein 70B’ (HSP70B’) gene expression as a stress response marker.

権利情報:

• Creative Commons BY Attribution 4.0 International
  

キーワード: Heat Shock Protein 70B’, cytocompatibility, human osteoblast-like SaOS-2 cells, human monocyte THP-1 cells

刊行年月日: 2007-06-20

出版者: Bentham Science Publishers Ltd.

掲載誌:

• The Open Biotechnology Journal (ISSN: 18740715) vol. 1 p. 14-17

研究助成金:

原稿種別: 出版者版 (Version of record)

MDR DOI:

公開URL: https://doi.org/10.2174/1874070700701010014

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更新時刻: 2025-09-18 12:30:21 +0900

MDRでの公開時刻: 2025-09-18 12:23:06 +0900