Ayaka Kadotani
;
Gen Hayase
(National Institute for Materials Science
)
;
Daisuke Yoshino
Collection
Citation
Description:
(abstract)細胞の種類や細胞外マトリックス、接着成分に依存しない様々な形状のオルガノイドユニットの作製、連結、組み立て方法（ユニット構築法）を確立した。また、ヒトの腎臓を構成する3種類の実質細胞と間質細胞を用いて腎組織様構造を作製し、ユニット間のクロストークの可能性を示唆する知見を得た。
Description:
(abstract)We established a method for fabricating, connecting, and assembling organoid units of various shapes independent of cell type, extracellular matrix, and adhesive composition (unit construction method). We also fabricated kidney tissue-like structures using three types of parenchymal and interstitial cells that compose the human kidney and obtained findings suggesting the possibility of crosstalk between the units.
Rights:
Keyword: tissue engineering, superhydrophobic substrate, organoid, unit construction method
Date published: 2024-12-01
Publisher: AIP Publishing
Journal:
- APL Bioengineering (ISSN: 24732877) vol. 8 issue. 4 046112
Funding:
- Japan Society for the Promotion of Science 21K19893
- Japan Science and Technology Agency JPMJFR222S
- National Institute for Materials Science 2023-097
Manuscript type: Publisher's version (Version of record)
MDR DOI:
First published URL: https://doi.org/10.1063/5.0222866
Related item:
Other identifier(s):
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Updated at: 2024-12-03 16:31:14 +0900
Published on MDR: 2024-12-03 16:31:15 +0900
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