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説明:

Artificially designed, functional nanostructured surfaces, called metasurfaces, are an emerging platform for biosensing. Two major types of metasurface biosensors have been reported: one is based on resonant-wavelength shift and the other is specialized for fluorescence (FL) detection. The all-dielectric metasurfaces that composed of periodic arrays of silicon nanocolumns have a series of optical magnetic-mode resonances, some of which were found to significantly enhance capability for FL detection of diverse target biomolecules, ranging from nucleic acid to antigens and antibodies. Here, we mainly address the recent advances in productive metasurface FL biosensors, provide an overview of the pivotal results, and discuss the future prospects, including artificial-intelligence-driven big data analysis for the next-generation healthcare services.

権利情報:

• Creative Commons BY Attribution 4.0 International
  

キーワード: all-dielectric metasurface, fluorescence, biosensor, DNA, antibody, antigen, big data

刊行年月日: 2025-01-09

出版者: Frontiers Media SA

掲載誌:

• Frontiers in Bioengineering and Biotechnology (ISSN: 22964185) vol. 12 1484638

研究助成金:

• NIMS (Priority Research Project "Biomaterials")

原稿種別: 出版者版 (Version of record)

MDR DOI:

公開URL: https://doi.org/10.3389/fbioe.2024.1484638

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更新時刻: 2025-12-24 11:53:54 +0900

MDRでの公開時刻: 2025-12-24 16:20:28 +0900