Article Analytical modeling and decoupling of humidity effects in nanomechanical sensing based on sorption kinetics and viscoelastic stress relaxation

Meng-Qun Feng SAMURAI ORCID ; Kosuke Minami SAMURAI ORCID ; Yingcheng Zhou SAMURAI ORCID ; Genki Yoshikawa SAMURAI ORCID

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Citation
Meng-Qun Feng, Kosuke Minami, Yingcheng Zhou, Genki Yoshikawa. Analytical modeling and decoupling of humidity effects in nanomechanical sensing based on sorption kinetics and viscoelastic stress relaxation. Physical Review E. 2025, 111 (6), 065407. https://doi.org/10.1103/physreve.111.065407

Description:

(abstract)

Nanomechanical sensors have gained significant attention as powerful tools for detecting target analytes; however, their signals are often influenced by environmental humidity. In static mode operation, the sensing signals of nanomechanical sensors are obtained by a concentration-dependent sorption-induced mechanical strain/stress. In this study, we derive an analytical model to describe the response of viscoelastic material-coated nanomechanical sensors by incorporating humidity effects based on sorption kinetics and viscoelastic stress relaxation of receptor materials. This model is capable of reproducing the dynamic responses observed in the experiments under varying humidity conditions. Moreover, it allows for the subtraction of humidity effects, facilitating the precise isolation of analyte-specific signals. These results provide a theoretical framework for decoupling environmental background factors, such as humidity effects, in nanomechanical sensors.

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Keyword: nanomechanical sensors, sorption kinetics, viscoelastic stress relaxation, humidity

Date published: 2025-06-09

Publisher: American Physical Society (APS)

Journal:

  • Physical Review E (ISSN: 24700045) vol. 111 issue. 6 065407

Funding:

  • Japan Society for the Promotion of Science 18H04168
  • Japan Society for the Promotion of Science 22K05324
  • Japan Society for the Promotion of Science 20K20554
  • Japan Society for the Promotion of Science JPMJSP2124
  • Japan Science and Technology Corporation
  • Ministry of Education, Culture, Sports, Science and Technology

Manuscript type: Author's version (Accepted manuscript)

MDR DOI: https://doi.org/10.48505/nims.5907

First published URL: https://doi.org/10.1103/physreve.111.065407

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Updated at: 2025-11-13 16:30:30 +0900

Published on MDR: 2025-11-13 16:24:25 +0900

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Filename AIP_humidity_SI.pdf
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