Article Effect of Alaska pollock-gelatin sheet on repair strength and regeneration of nerve

Ryosuke Tsujisaka ; Taku Suzuki ORCID ; Shinsuke Shibata ; Takuji Iwamoto ; Tetsushi Taguchi SAMURAI ORCID ; Masaya Nakamura

MDR Effect of Alaska pollock-gelatin sheet.pdf
Download file (1.43 MB)
Download as zip (1.38 MB)
Collection

Citation
Ryosuke Tsujisaka, Taku Suzuki, Shinsuke Shibata, Takuji Iwamoto, Tetsushi Taguchi, Masaya Nakamura. Effect of Alaska pollock-gelatin sheet on repair strength and regeneration of nerve. Journal of Hand Surgery (European Volume). 2024, 50 (1), 76-84. https://doi.org/10.1177/17531934241251670

Description:

(abstract)

This study aimed to investigate the bonding strength and the biocompatibility of Alaska pollock-derived gelatin (ApGltn) sheet. Cadaveric digital nerves were repaired with double suture, single suture + ApGltn sheet, single suture + fibrin, single suture, ApGltn sheet, and fibrin, and maximum failure loads were measured (20 nerves each). The rat sciatic nerves were exposed to double suture, single suture + ApGltn sheet, single
suture, ApGltn sheet, fibrin, and resection (10 nerves each). Macroscopic appearance, muscle weight, and histopathological findings were examined 8 weeks postoperatively. The failure load of ApGltn sheet (0.39 N) was significantly higher than that of a fibrin (0.05 N). The failure load of single suture + ApGltn sheet (1.32 N) was significantly higher than that of a single suture (0.97 N). Functional and histological examinations showed similar recovery among sutures, ApGltn, and fibrin groups. ApGltn sheet is useful for clinical application as an alternative to fibrin.

Rights:

  • In Copyright

    © The Author(s) 2024.
    The article is protected by copyright and reuse is restricted to non-commercial and no derivative uses.
    Tsujisaka R, Suzuki T, Shibata S, Iwamoto T, Taguchi T, Nakamura M. Effect of Alaska pollock-gelatin sheet on repair strength and regeneration of nerve. Journal of Hand Surgery (European Volume). 2024;50(1):76-84. doi:10.1177/17531934241251670

Keyword: Alaska pollock-derived gelatin, Sheet

Date published: 2024-05-23

Publisher: SAGE Publications

Journal:

  • Journal of Hand Surgery (European Volume) (ISSN: 17531934) vol. 50 issue. 1 p. 76-84

Funding:

  • Japan Society for the Promotion of Science 22K09364

Manuscript type: Author's version (Accepted manuscript)

MDR DOI: https://doi.org/10.48505/nims.5426

First published URL: https://doi.org/10.1177/17531934241251670

Related item:

Other identifier(s):

Contact agent:

Updated at: 2025-04-16 16:30:17 +0900

Published on MDR: 2025-04-16 14:29:31 +0900

Filename Size
Filename MDR Effect of Alaska pollock-gelatin sheet.pdf (Thumbnail)
application/pdf 		Size 1.43 MB Detail