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説明:

This study aimed to investigate the bonding strength and the biocompatibility of Alaska pollock-derived gelatin (ApGltn) sheet. Cadaveric digital nerves were repaired with double suture, single suture + ApGltn sheet, single suture + fibrin, single suture, ApGltn sheet, and fibrin, and maximum failure loads were measured (20 nerves each). The rat sciatic nerves were exposed to double suture, single suture + ApGltn sheet, single
suture, ApGltn sheet, fibrin, and resection (10 nerves each). Macroscopic appearance, muscle weight, and histopathological findings were examined 8 weeks postoperatively. The failure load of ApGltn sheet (0.39 N) was significantly higher than that of a fibrin (0.05 N). The failure load of single suture + ApGltn sheet (1.32 N) was significantly higher than that of a single suture (0.97 N). Functional and histological examinations showed similar recovery among sutures, ApGltn, and fibrin groups. ApGltn sheet is useful for clinical application as an alternative to fibrin.

権利情報:

• In Copyright
  

  © The Author(s) 2024.
  The article is protected by copyright and reuse is restricted to non-commercial and no derivative uses.
  Tsujisaka R, Suzuki T, Shibata S, Iwamoto T, Taguchi T, Nakamura M. Effect of Alaska pollock-gelatin sheet on repair strength and regeneration of nerve. Journal of Hand Surgery (European Volume). 2024;50(1):76-84. doi:10.1177/17531934241251670

キーワード: Alaska pollock-derived gelatin, Sheet

刊行年月日: 2024-05-23

出版者: SAGE Publications

掲載誌:

• Journal of Hand Surgery (European Volume) (ISSN: 17531934) vol. 50 issue. 1 p. 76-84

研究助成金:

• Japan Society for the Promotion of Science 22K09364

原稿種別: 著者最終稿 (Accepted manuscript)

MDR DOI: https://doi.org/10.48505/nims.5426

公開URL: https://doi.org/10.1177/17531934241251670

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更新時刻: 2025-04-16 16:30:17 +0900

MDRでの公開時刻: 2025-04-16 14:29:31 +0900