Article 3D printed scaffold based on polycaprolactone/self-assembled fullerene (C60) nanorod for bone tissue engineering

Novi Dwi Widya Rini SAMURAI ORCID ; Adel Alshammari ; Candrani Khoirinaya ; Anggraini Barlian ; Lia A. T. W. Asri ; Glen Cooper ; Katsuhiko Ariga SAMURAI ORCID ; Lok Kumar Shrestha SAMURAI ORCID ; Arie Wibowo ORCID

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Citation
Novi Dwi Widya Rini, Adel Alshammari, Candrani Khoirinaya, Anggraini Barlian, Lia A. T. W. Asri, Glen Cooper, Katsuhiko Ariga, Lok Kumar Shrestha, Arie Wibowo. 3D printed scaffold based on polycaprolactone/self-assembled fullerene (C60) nanorod for bone tissue engineering. Emergent Materials. 2024, 8 (3), 1781-1795. https://doi.org/10.1007/s42247-024-00924-6

Description:

(abstract)

3D printed polycaprolactone (PCL)-based scaffolds have garnered attention in bone tissue engineering due to their biocompatibility, biodegradability, and precise geometry control. However, it is yet challenging to tune the mechanical properties and hydrophilicity. This paper reports a subtle balance between the mechanical properties and hydrophilicity of the scaffold essential in bone tissue engineering using self-assembled fullerene (C60) nanorods (FNR) and Pluronic 123 surface-modified fullerene nanorods (PFNR) as the reinforced filler. The antibacterial activity results reveal that FNR without surface modification offers better antibacterial activity than PFNR, particularly against Staphylococcus aureus and Escherichia coli.

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  • In Copyright

    This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s42247-024-00924-6

Keyword: 3D printing, Bone tissue engineering, Fullerene nanorod, Hydrophilicity, Polycaprolactone

Date published: 2024-11-22

Publisher: Springer Science and Business Media LLC

Journal:

  • Emergent Materials (ISSN: 25225731) vol. 8 issue. 3 p. 1781-1795

Funding:

Manuscript type: Author's version (Accepted manuscript)

MDR DOI: https://doi.org/10.48505/nims.5612

First published URL: https://doi.org/10.1007/s42247-024-00924-6

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Updated at: 2025-11-22 08:30:03 +0900

Published on MDR: 2025-11-22 08:22:50 +0900

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