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説明:

3D printed polycaprolactone (PCL)-based scaffolds have garnered attention in bone tissue engineering due to their biocompatibility, biodegradability, and precise geometry control. However, it is yet challenging to tune the mechanical properties and hydrophilicity. This paper reports a subtle balance between the mechanical properties and hydrophilicity of the scaffold essential in bone tissue engineering using self-assembled fullerene (C60) nanorods (FNR) and Pluronic 123 surface-modified fullerene nanorods (PFNR) as the reinforced filler. The antibacterial activity results reveal that FNR without surface modification offers better antibacterial activity than PFNR, particularly against Staphylococcus aureus and Escherichia coli.

権利情報:

• In Copyright
  This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s42247-024-00924-6

キーワード: 3D printing, Bone tissue engineering, Fullerene nanorod, Hydrophilicity, Polycaprolactone

刊行年月日: 2024-11-22

出版者: Springer Science and Business Media LLC

掲載誌:

• Emergent Materials (ISSN: 25225731) vol. 8 issue. 3 p. 1781-1795

研究助成金:

原稿種別: 著者最終稿 (Accepted manuscript)

MDR DOI: https://doi.org/10.48505/nims.5612

公開URL: https://doi.org/10.1007/s42247-024-00924-6

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更新時刻: 2025-11-22 08:30:03 +0900

MDRでの公開時刻: 2025-11-22 08:22:50 +0900