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Description:

Delayed bleeding following endoscopic mucosal resection or endoscopic submucosal dissection is a serious concern in patients receiving anticoagulant therapy. We previously established an experimental animal model of delayed gastric bleeding following endoscopic resection under controlled anticoagulation. In this study, we aimed to evaluate the potential preventive effect of hydrophobized microparticles (hMPs), a novel sprayable wound-covering material derived from Alaska pollock gelatin, in preventing delayed bleeding.

Rights:

• Creative Commons BY Attribution 4.0 International
  

Keyword: Endoscopic submucosal dissection, Endoscopic mucosal resection, Delayed gastric bleeding, Anticoagulation therapy, Hydrophobized microparticlesl, animal mode

Date published: 2026-02-03

Publisher: Springer Science and Business Media LLC

Journal:

• Scientific Reports (ISSN: 20452322) vol. 16 issue. 1 7075

Funding:

• Japan Society for the Promotion of Science KAKENHI
• Japan Agency of Medical Research and Development

Manuscript type: Author's version (Accepted manuscript)

MDR DOI: https://doi.org/10.48505/nims.6218

First published URL: https://doi.org/10.1038/s41598-026-38423-9

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Updated at: 2026-03-16 09:03:32 +0900

Published on MDR: 2026-03-16 17:54:54 +0900