Quantitative Fluorescent Detection of Antibacterial Activity with Pyrene-Bearing Tannic Acid

Takehiro Fujita; Jun Hasegawa; Miki Onoue; Ryohei Matsubara; Takako Yamamoto; Masanobu Naito

doi:10.1246/bcsj.20220046

論文 Quantitative Fluorescent Detection of Antibacterial Activity with Pyrene-Bearing Tannic Acid

Takehiro Fujita (Research and Services Division of Materials Data and Integrated System, National Institute for Materials Science) ; Jun Hasegawa (Development Strategy Department, Technology Innovation Center, Business Development Division, TOPPAN INC) ; Miki Onoue (Research and Services Division of Materials Data and Integrated System, National Institute for Materials Science) ; Ryohei Matsubara (Development Strategy Department, Technology Innovation Center, Business Development Division, TOPPAN INC) ; Takako Yamamoto (Development Strategy Department, Technology Innovation Center, Business Development Division, TOPPAN INC) ; Masanobu Naito (Research and Services Division of Materials Data and Integrated System, National Institute for Materials Science)

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引用

Takehiro Fujita, Jun Hasegawa, Miki Onoue, Ryohei Matsubara, Takako Yamamoto, Masanobu Naito. Quantitative Fluorescent Detection of Antibacterial Activity with Pyrene-Bearing Tannic Acid. Bulletin of the Chemical Society of Japan. 2022, 95 (5), 748-750. https://doi.org/10.1246/bcsj.20220046

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(abstract)

Quantitative evaluation of the antibacterial activity of conventional antibacterial agents in situ is difficult. In this study, we demonstrated that antibacterial activity can be quantitatively estimated from the photoluminescence intensity of pyrene fluorophores incorporated into tannic acid, a naturally occurring antibacterial agent.

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