# Fileset

[Effects of Synthetic Toll--2024-Quispe-Salced1.pdf](https://mdr.nims.go.jp/filesets/c649ce23-814a-4b5e-a985-f77d7274882b/download)

## Creator

Angela Quispe-Salcedo, [Tomohiko Yamazaki](https://orcid.org/0000-0003-2136-8042), Hayato Ohshima

## Rights

[Creative Commons BY Attribution 4.0 International](https://creativecommons.org/licenses/by/4.0/)

## Other metadata

[Effects of Synthetic Toll-Like Receptor 9 Ligand Molecules on Pulpal Immunomodulatory Response and Repair after Injuries](https://mdr.nims.go.jp/datasets/6bcb73d3-df2b-4c97-b074-9bcc47e64e4c)

## Fulltext

Figure S1: Histological evaluation of samples treated with HBSS at week 1  Figure S2: Histological evaluation of samples treated with HBSS at week 2  Figure S3: F4/80 and CD206 immunohistochemistry in samples of DW and HBSS groups at weeks 1 and 2;      Figure S4: The percentage of F4/80-positive area in the dental pulp;    Figure S5: The percentage of TLR9-positive area in the dental pulp;    Figure S6: The penetration of GFP-conjugated synthetic CpG-ODNs in the pulpal tissue; Table S1: The distribution of animals per experimental group. 1  Table S1. The distribution of animals per experimental group. Experimental solution Concentration Observation period Number of animals Number of teeth (n) DW – 1w 2w 5 6 10 12 HBSS 1x 1w 2w 6 6 12 12 CpG-ODN A 0.63 mg/ml (0.1 mM) 1w 2w 9 11 18 22 5 mg/ml (0.8 mM) 1w 2w 6 7 13 14 CpG-ODN B 0.63 mg/ml (0.1 mM) 1w 2w 10 11 20 22 5 mg/ml (0.8 mM) 1w 2w 7 8 14 16