# Hexagonal Boron Nitride Spacers for Fluorescence Imaging of Biomolecules

https://mdr.nims.go.jp/datasets/fa43d2ab-6368-4b23-bc7a-bbc1e8bc3b8a

## File

- [ChemNanoMat - 2024 - Yang - Hexagonal Boron Nitride Spacers for Fluorescence Imaging of Biomolecules.pdf](https://mdr.nims.go.jp/filesets/642872c6-8dcf-4547-9f04-d6d57ceb25a1/download) ([Detail](https://mdr.nims.go.jp/filesets/642872c6-8dcf-4547-9f04-d6d57ceb25a1.md))

## Id

fa43d2ab-6368-4b23-bc7a-bbc1e8bc3b8a

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-02-14T01:19:59.310406Z

## Updated at

2025-02-14T03:32:02.337342Z

## Published at

2025-02-14T03:32:02.405195Z

## Doi



## First published url

https://doi.org/10.1002/cnma.202300592

## Date published

2024-03-08

## Recorded date published

2024-5

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Hexagonal Boron Nitride Spacers for Fluorescence Imaging of Biomolecules
  title_type: original
  lang: en

## Description

- description: Here, we employ few-layer hexagonal boron nitride (hBN) as a precisely
    tailorable fluorescence spacer between labelled lipid membranes and graphene substrates.
    By stacking high-quality hBN crystals in the 10–20 nm thickness range on monolayer
    graphene, we observe distance-dependent fluorescence intensity variations. Remarkably,
    with hBN spacers as thin as 20nm, the fluorescence intensity is comparable to
    bare SiO2/Si substrates, while the intensity was reduced to 60 % and 80 % with
    ~10 nm and ~16 nm hBN thicknesses respectively. We confirm that pre- determined
    hBN thicknesses can be employed to control the non-radiative energy transfer properties
    of graphene, with fluorescence quenching following a d^-4 distance-dependent behaviour.
    This seamless integration of electronically active and dielectric van der Waals
    materials into vertical heterostructures enables multifunctional platforms addressing
    the manipulation, localization, and visualization of biomolecules for fundamental
    biophysics and biosensing applications.
  description_type: abstract
  lang: und

## Creator

- name: Xiliang Yang
  role: author
- name: Dong Hoon Shin
  role: author
- name: Ze Yu
  role: author
- name: Kenji Watanabe
  role: author
  orcid: https://orcid.org/0000-0003-3701-8119
  organization: National Institute for Materials Science
  ror: https://ror.org/026v1ze26
- name: Takashi Taniguchi
  role: author
  orcid: https://orcid.org/0000-0002-1467-3105
  organization: National Institute for Materials Science
  ror: https://ror.org/026v1ze26
- name: Vitaliy Babenko
  role: author
- name: Stephan Hofmann
  role: author
- name: Sabina Caneva
  role: author

## Contact agent



## Publisher

organization: Wiley

## Managing organization



## Keyword

- subject: Fluorescence imaging
  schema: not_defined
- subject: biomolecular dynamics
  schema: not_defined
- subject: hBN
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: ChemNanoMat
  issn: 2199692X
  volume: '10'
  issue: '5'
  article_number: e202300592

## Conference



## Related item



## Funding

- identifier: MechanoPore
  funder_name: Nederlandse Organisatie voor Wetenschappelijk Onderzoek

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 642872c6-8dcf-4547-9f04-d6d57ceb25a1
  filename: ChemNanoMat - 2024 - Yang - Hexagonal Boron Nitride Spacers for Fluorescence
    Imaging of Biomolecules.pdf
  content_type: application/pdf
  size: 1733028
  md5: da451ce876d9f7983d9d59ea578bd2d3

## Thumbnail

fileset_id: 642872c6-8dcf-4547-9f04-d6d57ceb25a1
filename: ChemNanoMat - 2024 - Yang - Hexagonal Boron Nitride Spacers for Fluorescence
  Imaging of Biomolecules.pdf