# Biocompatible pH sensor based on chitosan IPNs and polystyrene colloidal photonic crystal films

https://mdr.nims.go.jp/datasets/f4d9b12f-9d5c-4723-9e0c-59c4f9948643

## File

- [Manuscript SPIE 2025.docx](https://mdr.nims.go.jp/filesets/4ded544f-3c39-4547-a68c-8893adf07bec/download) ([Detail](https://mdr.nims.go.jp/filesets/4ded544f-3c39-4547-a68c-8893adf07bec.md))

## Id

f4d9b12f-9d5c-4723-9e0c-59c4f9948643

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-04-02T00:04:18.839220Z

## Updated at

2025-04-02T07:30:12.959284Z

## Published at

2025-04-02T08:21:14.077927Z

## Doi

https://doi.org/10.48505/nims.5397

## First published url

https://doi.org/10.1117/12.3042321

## Date published

2025-03-21

## Recorded date published

2025-3-21

## Resource type

conference_paper

## Manuscript type

accepted_manuscript

## Collection



## Title

- title: Biocompatible pH sensor based on chitosan IPNs and polystyrene colloidal
    photonic crystal films
  title_type: original
  lang: en

## Description

- description: Our research involves the fabrication of a pH-sensitive Chitosan-Tetraethyl
    orthosilicate-Glutaraldehyde Interpenetrating Polymer Network (Chi-TEOS-GA IPN)
    suitable for combination with polystyrene (PS) colloidal photonic crystal films
    to produce a device capable of showing a visual color change in response to a
    change in pH. The pH-sensitive properties of chitosan occur naturally due to its
    cationic polyelectrolyte structure. Cross-linking chitosan with TEOS and GA increases
    mechanical strength and PS photonic crystal films provide the means of optical
    detection. Monodisperse PS particles with various sizes were synthesized by emulsion
    polymerization of a styrene monomer in the presence of sodium dodecyl sulfate
    (SDS) as a surfactant. The PS colloid suspension was vertically deposited onto
    the flexible silicon rubber sheet to make a PS photonic crystal film. The closely
    packed PS particles were infilled and cured multiple times with polydimethylsiloxane
    (PDMS) elastomer, which allows for reversible color change by elastic deformation.
    All Chi-TEOS-GA films were prepared by drop casting with constant experimental
    conditions such as temperature, substrate, and time. Chi-TEOS-GA films swelling
    studies show an increase in the size and weight of the films with decreasing pH.
    The PS photonic crystal films were put on top of the pH-sensitive films and enclosed
    in a solid frame to prevent swelling in unwanted directions. Investigation of
    spectrometry measurements shows a shift of the spectra to lower wavelengths with
    decreasing pH, resulting in a color change of the PS photonic crystal film. These
    results are discussed in terms of the potential use of this device in biomedical
    applications, such as wound dressings.
  description_type: abstract
  lang: und

## Creator

- name: Lubos Podlucky
  role: author
- name: Hiroshi Fudouzi
  role: author
  orcid: https://orcid.org/0000-0003-1442-4667
- name: Maria Bardosova
  role: author
- name: Marek Osiński
  role: editor
- name: Antonios G. Kanaras
  role: editor

## Contact agent



## Publisher

organization: SPIE

## Managing organization



## Keyword

- subject: photonic crystals
  schema: not_defined
- subject: chitosan
  schema: not_defined
- subject: pH sensing
  schema: not_defined
- subject: photonic rubber
  schema: not_defined
- subject: interpenetrating polymer network
  schema: not_defined

## Rights

- description: Copyright 2025 Society of Photo‑Optical Instrumentation Engineers (SPIE).
    One print or electronic copy may be made for personal use only. Systematic reproduction
    and distribution, duplication of any material in this publication for a fee or
    for commercial purposes, and modification of the contents of the publication are
    prohibited.
  identifier: http://rightsstatements.org/vocab/InC/1.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Colloidal Nanoparticles for Biomedical Applications XX
  volume: '13336'
  article_number: '1333607'

## Conference



## Related item



## Funding



## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 4ded544f-3c39-4547-a68c-8893adf07bec
  filename: Manuscript SPIE 2025.docx
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  size: 425931
  md5: 3d4354301722f8832bc8eb88106ab087

## Thumbnail

fileset_id: 4ded544f-3c39-4547-a68c-8893adf07bec
filename: Manuscript SPIE 2025.docx