# Investigating the Effect of Thickener Concentrations on the Corrosion Behavior of Pure Mg

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## File

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## Id

f2be341b-0181-4186-b7a3-93c96421043d

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-03-26T04:54:27.193707Z

## Updated at

2025-03-27T08:43:59.117672Z

## Published at

2025-03-27T08:44:00.610148Z

## Doi



## First published url

https://doi.org/10.1002/jbm.a.37878

## Date published

2025-02-02

## Recorded date published

2025-2

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Investigating the Effect of Thickener Concentrations on the Corrosion Behavior
    of Pure Mg
  title_type: original
  lang: en

## Description

- description: 'Magnesium (Mg) and its alloys are promising biodegradable implant
    materials due to their biocompatibility, and ease of corrosion in physiological
    environment. In the tissue, diffusion of ions and gas released by Mg corrosion
    reaction will be interfered by extracellular matrix and cells, which may retard
    the corrosion reaction. Therefore, in the present study, we developed the in vitro
    model tissue with different diffusion rates to understand the effect of diffusion
    on the Mg corrosion. A thickener called gellan gum was added to the cell culture
    medium at appropriate concentrations to simulate tissues with different diffusion
    rates. The immersion study up to 28 days and the electrochemical studies were
    performed to evaluate the Mg corrosion behaviour.  The pure Mg specimens without
    thickener showed the highest corrosion rate in both immersion and electrochemical
    tests. The highest amount of insoluble salt layer with the lowest Mg and highest
    O concentrations were deposited on the specimen surface without thickener. The
    microfocus X-ray computer tomography (µCT) analysis confirmed these findings,
    showing the lowest remaining volume for specimens without thickener. There is
    an impediment of ion diffusion in the model tissue with increased thickener concentrations,
    thereby decreasing the corrosion rate. The corrosion rate for 0.2-0.3 wt. % thickener
    matched in the range of reported in vivo results. Hence, this model proves to
    be an effective tool for investigating biodegradation and understanding the mechanisms
    and controlling factors of this phenomenon. '
  description_type: abstract
  lang: und

## Creator

- name: Manas Ranjan Sahu
  role: author
  orcid: https://orcid.org/0009-0009-6467-8420
  organization: National Institute for Materials Science
- name: Akiko Yamamoto
  role: author
  orcid: https://orcid.org/0000-0002-9182-4886
  organization: National Institute for Materials Science

## Contact agent



## Publisher

organization: Wiley

## Managing organization



## Keyword

- subject: Potentiodynamic polarization
  schema: not_defined
- subject: pure Mg
  schema: not_defined
- subject: in vitro model tissue
  schema: not_defined
- subject: biodegradable metals
  schema: not_defined
- subject: electrochemical impedance spectroscopy
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by-nc-nd/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Journal of Biomedical Materials Research Part A
  issn: '15493296'
  volume: '113'
  issue: '2'

## Conference



## Related item



## Funding

- funder_name: Japan Society for the Promotion of Science
- funder_name: Ministry of Education, Culture, Sports, Science and Technology

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: dea94e20-1dfa-4a73-bd47-5936149eae94
  filename: Investigating the Effect of Thickener Concentrations on the Corrosion
    Behavior of Pure Mg.pdf
  content_type: application/pdf
  size: 1824285
  md5: eafa6f6400b570f0a1f43f1846b9876e
- id: 720fffc8-9606-47b6-be5e-09a7c823ff94
  filename: R1. JBMRA_S1.pdf
  content_type: application/pdf
  size: 208348
  md5: 6b72c0b03e6f1166a511bcfcecedf6bd

## Thumbnail

fileset_id: 720fffc8-9606-47b6-be5e-09a7c823ff94
filename: R1. JBMRA_S1.pdf