# Development of Layer-by-Layer Magnetic Nanoparticles for Application to Radiotherapy of Pancreatic Cancer

https://mdr.nims.go.jp/datasets/f09032d9-b87f-4708-9aa4-49ca4892e620

## File

- [25_Molecules.pdf](https://mdr.nims.go.jp/filesets/c4823e34-0aad-4a46-8b1f-7f68dc45f42b/download) ([Detail](https://mdr.nims.go.jp/filesets/c4823e34-0aad-4a46-8b1f-7f68dc45f42b.md))

## Id

f09032d9-b87f-4708-9aa4-49ca4892e620

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-05-28T10:33:57.226322Z

## Updated at

2026-01-06T06:51:34.605884Z

## Published at

2026-01-06T23:24:33.330524Z

## Doi



## First published url

https://doi.org/10.3390/molecules30061382

## Date published

2025-03-20

## Recorded date published



## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Development of Layer-by-Layer Magnetic Nanoparticles for Application to Radiotherapy
    of Pancreatic Cancer
  title_type: original
  lang: en

## Description

- description: 'This study introduces a novel drug delivery system using gemcitabine
    (GEM)-loaded layer-by-layer magnetic nanoparticles (LBL MNPs) combined with alternating
    magnetic field (AMF) application and X-ray irradiation to enhance therapeutic
    efficacy. '
  description_type: abstract
  lang: und

## Creator

- name: Nobuyoshi Fukumitsu
  role: author
- name: Yoshitaka Matsumoto
  role: author
- name: Lili Chen
  role: author
  organization: National Institute for Materials Science
- name: Yu Sugawara
  role: author
- name: Nanami Fujisawa
  role: author
  orcid: https://orcid.org/0000-0002-8894-1790
  organization: National Institute for Materials Science
- name: Eri Niiyama
  role: author
- name: Sosuke Ouchi
  role: author
  organization: National Institute for Materials Science
- name: Emiho Oe
  role: author
  organization: National Institute for Materials Science
- name: Takashi Saito
  role: author
- name: Mitsuhiro Ebara
  role: author
  orcid: https://orcid.org/0000-0002-7906-0350
  organization: National Institute for Materials Science

## Contact agent



## Publisher

organization: MDPI AG

## Managing organization



## Keyword

- subject: Layer by layer
  schema: not_defined
- subject: Magnetic nanoparticle
  schema: not_defined
- subject: Radiotherapy
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Molecules
  issn: '14203049'
  volume: '30'
  issue: '6'
  article_number: '1382'

## Conference



## Related item



## Funding

- identifier: JP15K19768
  funder_name: JSPS KAKENHI
- identifier: JP17K15016
  funder_name: JSPS KAKENHI
- identifier: TK20-044
  funder_name: JSPS KAKENHI
- identifier: JP15K19768
  funder_name: Tsukuba Innovation Arena (TIA) Collaborative Program Exploration and
    Promotion Project Kakehashi
- identifier: JP17K15016
  funder_name: Tsukuba Innovation Arena (TIA) Collaborative Program Exploration and
    Promotion Project Kakehashi
- identifier: TK20-044
  funder_name: Tsukuba Innovation Arena (TIA) Collaborative Program Exploration and
    Promotion Project Kakehashi

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: c4823e34-0aad-4a46-8b1f-7f68dc45f42b
  filename: 25_Molecules.pdf
  content_type: application/pdf
  size: 2750707
  md5: 11134f7a0bf689c882a7aae69ed7dfc6

## Thumbnail

fileset_id: c4823e34-0aad-4a46-8b1f-7f68dc45f42b
filename: 25_Molecules.pdf