説明:
(abstract)Fine-particle bombardment (FPB) is typically used to modify metal surfaces by bombarding them with fine particles at high speed. FPB is not a coating technique but is used for forming microscale concavities and convexities on a surface. Previously, we reported that an FPB-treated surface showed antibacterial effects; however, the underlying mechanisms remain unclear. We hypothesized that the pitch size of concavity and convexity, and irregular microscale pattern of FPB-treated surfaces might contribute to the antibacterial performance. In this study, we applied FPB to stainless-steel surfaces and evaluated the antibacterial effects of the FPB-treated surfaces based on ISO 22,196:2007. The FPB-treated surfaces exhibited antibacterial activity against Escherichia coli, with an antibacterial activity value (R) of two or more. Furthermore, our experiments suggest that the antibacterial mechanism of the FPB-treated surface can be attributed to increased oxidative stress in bacteria owing to physical stress from the rough surface. The antibacterial effect of FPB-treated surfaces offers an effective measure against drug-resistant bacteria.
権利情報:
キーワード: Fine particle bombarding, surface shape, antibacterial effect, oxidative stress
刊行年月日: 2024-12-31
出版者: Taylor & Francis
掲載誌:
研究助成金:
原稿種別: 著者最終稿 (Accepted manuscript)
MDR DOI: https://doi.org/10.48505/nims.4702
公開URL: https://doi.org/10.1080/14686996.2024.2376522
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更新時刻: 2025-07-16 16:14:46 +0900
MDRでの公開時刻: 2024-08-30 08:30:16 +0900
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Mechanism of antibacterial property of micro scale rough surface formed by fine-particle bombarding.pdf
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