# Figures of merit and screening approaches for evaluating heat generation in magnetic nanoparticles for hyperthermia

https://mdr.nims.go.jp/datasets/e91b4a24-58cd-4cf2-bbd9-f841a17803ee

## File

- [2026 Materials_Today_Nano_Figures of merit and screening approaches for evaluating heat generation in magnetic nanoparticles for hyperthermia.pdf](https://mdr.nims.go.jp/filesets/cdec0bad-561d-4d81-bbdc-5ef5d567c23d/download) ([Detail](https://mdr.nims.go.jp/filesets/cdec0bad-561d-4d81-bbdc-5ef5d567c23d.md))

## Id

e91b4a24-58cd-4cf2-bbd9-f841a17803ee

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2026-06-26T01:39:12.217435Z

## Updated at

2026-06-26T01:43:39.808483Z

## Published at

2026-06-26T05:28:24.675540Z

## Doi



## First published url

https://doi.org/10.1016/j.mtnano.2026.100869

## Date published

2026-06-17

## Recorded date published

2026-8

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Figures of merit and screening approaches for evaluating heat generation
    in magnetic nanoparticles for hyperthermia
  title_type: original
  lang: en

## Description

- description: The heating performance of magnetic nanoparticles for hyperthermia
    is typically assessed by the specific absorption rate (SARnano), measured under
    laboratory-specific irradiation conditions. However, since SARnano depends heavily
    on magnetic field amplitude and frequency, comparing material performance across
    studies is challenging. This study introduces additional indicators, such as the
    heating selectivity ratio (which reflects side effects) and the specific power
    factor (device load), and demonstrates that the ratio of experimentally generated
    heat to theoretical maximum heat output is a more reliable metric for heat generation
    efficiency, independent of irradiation conditions. Conventional measurement conditions
    may not reveal nanoparticles with the highest heating potential, so a predictive
    method based on blocking temperature and switching field distribution was developed.
    This method accurately predicts heating behavior for immobilized nanoparticles
    but needs improvement to account for dipolar interactions and particle rotations.
    The proposed metrics and framework provide a more robust approach to evaluating
    nanoparticle performance for hyperthermia.
  description_type: abstract
  lang: und

## Creator

- name: Hiroaki Mamiya
  role: author
  orcid: https://orcid.org/0000-0002-7840-3008
- name: Balachandran Jeyadevan
  role: author
- name: Eiji Kita
  role: author
- name: Reisho Onodera
  role: author
- name: Tetsushi Taguchi
  role: author
- name: Nikita Kulesh
  role: author
- name: Hossein Sepehri Amin
  role: author

## Contact agent



## Publisher

organization: Elsevier BV

## Managing organization



## Keyword

- subject: Hyperthermia treatment
  schema: not_defined
- subject: Magnetic nanoparticle
  schema: not_defined
- subject: Magnetic heating efficiency
  schema: not_defined
- subject: Specific absorption rate
  schema: not_defined
- subject: Blocking temperature
  schema: not_defined
- subject: Switching field distribution
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin



## Embargo



## Journal

- title: Materials Today Nano
  issn: '25888420'
  volume: '35'
  article_number: '100869'

## Conference



## Related item



## Funding

- funder_name: Government of Japan Ministry of Education Culture Sports Science and
    Technology
- funder_name: Japan Society for the Promotion of Science

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: cdec0bad-561d-4d81-bbdc-5ef5d567c23d
  filename: 2026 Materials_Today_Nano_Figures of merit and screening approaches for
    evaluating heat generation in magnetic nanoparticles for hyperthermia.pdf
  content_type: application/pdf
  size: 5584825
  md5: dfffca6810adbfa8fc189ca401c15a8a

## Thumbnail

fileset_id: cdec0bad-561d-4d81-bbdc-5ef5d567c23d
filename: 2026 Materials_Today_Nano_Figures of merit and screening approaches for
  evaluating heat generation in magnetic nanoparticles for hyperthermia.pdf