# Chemically-Fueled Phase Transition of a redox-responsive polymer

https://mdr.nims.go.jp/datasets/e0322ede-c608-4b57-9a90-ad371d45f974

## Files

- [Chemically-Fueled Phase Transition of a redox-responsive polymer.pdf](https://mdr.nims.go.jp/filesets/52f0fe69-ad73-4211-9954-dc87748d1440/download) ([Detail](https://mdr.nims.go.jp/filesets/52f0fe69-ad73-4211-9954-dc87748d1440.md))

## Id

e0322ede-c608-4b57-9a90-ad371d45f974

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-04-24T05:29:46.192426Z

## Updated at

2025-07-16T07:14:52.003273Z

## Published at

2025-04-24T23:22:33.942227Z

## Doi

https://doi.org/10.48505/nims.5453

## First published url

https://doi.org/10.1080/14686996.2025.2494496

## Date published

2025-12-31

## Recorded date published

2025-12-31

## Resource type

journal_article

## Manuscript type

accepted_manuscript

## Collection



## Title

- title: Chemically-Fueled Phase Transition of a redox-responsive polymer
  title_type: original
  lang: en

## Description

- description: In living systems, dynamic biomacromolecular assemblies are driven
    and regulated by energy dissipative chemical reaction networks, enabling various
    autonomous functions. Inspired by this biological principle, we report a chemically-fueled
    phase transition of a poly(N-isopropylacrylamide) (PNIPAAm)-based polymer bearing
    viologen units (P(NIPAAm-V)), wherein redox changes drive coil-to-globule phase
    transitions. Upon the addition of a reducing agent, viologen moieties in P(NIPAAm-V)
    are converted into their reduced state, resulting in enhanced hydrophobicity and
    polymer aggregation. Coexistence of a platinum catalyst couples these redox-driven
    structural changes to hydrogen evolution, which oxidizes the viologen radicals,
    thus restoring the polymer chains to their hydrated random coil state. As a result,
    transient polymer assemblies form and subsequently disassemble upon depletion
    of the reducing agent, leading to a temporally controlled out-of-equilibrium phase
    transition. Moreover, by tuning the platinum concentration and reaction temperature,
    we achieve precise control of both the size and lifetime of these assemblies.
    Notably, viologen moieties constitute only about 1% of the polymer repeating units,
    underscoring that chemically-fueled phase transition is efficient strategy for
    dynamically regulating molecular assemblies. These findings demonstrate that chemically-fueled
    phase transitions in redox-responsive polymers offer a promising blueprint for
    designing dynamic, biomimetic materials capable of spatiotemporally regulated
    structural transformations.
  description_type: abstract
  lang: en

## Creator

- name: Takafumi Enomoto
  role: author
  organization: The University of Tokyo
  department: a Department of Materials Engineering, School of Engineering
- name: Aya M. Akimoto
  role: author
- name: Ryo Yoshida
  role: author

## Contact agent



## Publisher

organization: Taylor & Francis

## Managing organization



## Keyword

- subject: Chemically-fueled self-assembly
  schema: not_defined
- subject: coil-to-globule phase transition
  schema: not_defined
- subject: poly(n-isopropylacrylamide)
  schema: not_defined
- subject: hydrogen evolution
  schema: not_defined
- subject: viologen
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by-nc/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Science and Technology of Advanced Materials
  issn: '14686996'
  volume: '26'
  article_number: '2494496'

## Conference



## Related item



## Funding



## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



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## Fileset

- id: 52f0fe69-ad73-4211-9954-dc87748d1440
  filename: Chemically-Fueled Phase Transition of a redox-responsive polymer.pdf
  content_type: application/pdf
  size: 1613370
  md5: b91b63290059d349643c990f678d3475

## Thumbnail

fileset_id: 52f0fe69-ad73-4211-9954-dc87748d1440
filename: Chemically-Fueled Phase Transition of a redox-responsive polymer.pdf