# Biofabrication of engineered blood vessels for biomedical applications

https://mdr.nims.go.jp/datasets/cf40929c-e94a-465e-9389-9a347a4e6fd6

## File

- [Biofabrication of engineered blood vessels for biomedical applications.pdf](https://mdr.nims.go.jp/filesets/88956f4e-4ddf-4336-9dcf-8d3b68bd8111/download) ([Detail](https://mdr.nims.go.jp/filesets/88956f4e-4ddf-4336-9dcf-8d3b68bd8111.md))

## Id

cf40929c-e94a-465e-9389-9a347a4e6fd6

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2024-04-02T05:31:26.655210Z

## Updated at

2024-04-04T23:30:14.532090Z

## Published at

2024-04-04T23:30:14.922328Z

## Doi

https://doi.org/10.48505/nims.4465

## First published url

https://doi.org/10.1080/14686996.2024.2330339

## Date published

2024-12-31

## Recorded date published

2024-12-31

## Resource type

journal_article

## Manuscript type

accepted_manuscript

## Collection



## Title

- title: Biofabrication of engineered blood vessels for biomedical applications
  title_type: original
  lang: en

## Description

- description: To successfully engineer large-sized tissues, establishing vascular
    structures is essential for providing oxygen, nutrients, growth factors and cells
    to prevent necrosis at the core of the tissue. The diameter scale of the biofabricated
    vasculatures should range from 100 to 1,000 µm to support the mm-size tissue while
    being controllably aligned and spaced within the diffusion limit of oxygen. In
    this review, insights regarding biofabrication considerations and techniques for
    engineered blood vessels will be presented. Initially, polymers of natural and
    synthetic origins can be selected, modified, and combined with each other to support
    maturation of vascular tissue while also being biocompatible. After they are shaped
    into scaffold structures by different fabrication techniques, surface properties
    such as physical topography, stiffness, and surface chemistry play a major role
    in the endothelialization process after transplantation. Furthermore, biological
    cues such as growth factors (GFs) and endothelial cells (ECs) can be incorporated
    into the fabricated structures. As variously reported, fabrication techniques,
    especially 3D printing by extrusion and 3D printing by photopolymerization, allow
    the construction of vessels at a high resolution with diameters in the desired
    range. Strategies to fabricate of stable tubular structures with defined channels
    will also be discussed. This paper provides an overview of the many advances in
    blood vessel engineering and combinations of different fabrication techniques
    up to the present time.
  description_type: abstract
  lang: en

## Creator

- name: Panitporn Laowpanitchakorn
  role: author
  organization: Malaysia–Japan International Institute of Technology
- name: Jinfeng Zeng
  role: author
- name: Marie Piantino
  role: author
  organization: Malaysia–Japan International Institute of Technology
- name: Kentaro Uchida
  role: author
- name: Misa Katsuyama
  role: author
- name: Michiya Matsusaki
  role: author
  organization: Osaka University
  department: Department of Applied Chemistry, Graduate School of Engineering

## Contact agent



## Publisher

organization: Taylor & Francis

## Managing organization



## Keyword

- subject: Blood vessel engineering
  schema: not_defined
- subject: biofabrication
  schema: not_defined
- subject: endothelialization
  schema: not_defined
- subject: 3D printing
  schema: not_defined
- subject: large-sized tissues
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by-nc/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Science and Technology of Advanced Materials
  issn: '14686996'
  volume: '25'
  article_number: '2330339'

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## Fileset

- id: 88956f4e-4ddf-4336-9dcf-8d3b68bd8111
  filename: Biofabrication of engineered blood vessels for biomedical applications.pdf
  content_type: application/pdf
  size: 3288185
  md5: 49ad6338284932e8de8d64c4ae767280

## Thumbnail

fileset_id: 88956f4e-4ddf-4336-9dcf-8d3b68bd8111
filename: Biofabrication of engineered blood vessels for biomedical applications.pdf