# Metasurface biosensors: Status and prospects

https://mdr.nims.go.jp/datasets/cd5a5931-931e-4d5d-99a0-0a890c94f976

## File

- [Iwanaga_et_al_ApplPhysRev12(2025)021305.pdf](https://mdr.nims.go.jp/filesets/52239f0e-7bbe-4f25-8c1b-caaa9d71d1bc/download) ([Detail](https://mdr.nims.go.jp/filesets/52239f0e-7bbe-4f25-8c1b-caaa9d71d1bc.md))

## Id

cd5a5931-931e-4d5d-99a0-0a890c94f976

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-04-07T03:36:39.502308Z

## Updated at

2025-04-07T23:30:08.678672Z

## Published at

2025-04-07T13:14:01.244361Z

## Doi



## First published url

https://doi.org/10.1063/5.0253333

## Date published

2025-06-01

## Recorded date published

2025-6-1

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: 'Metasurface biosensors: Status and prospects'
  title_type: original
  lang: en

## Description

- description: Metasurfaces have emerged as a rapidly evolving frontier in the fields
    of optics and photonics, with a growing emphasis on their potential for practical
    applications. The considerable volume of contributions to the study on metasurfaces
    has expanded, creating challenges in tracking all the advancements within this
    dynamic field. In this review, we select practically useful metasurfaces among
    the diverse metasurfaces studied so far. We refer to the selected hot research
    topics in metasurfaces at the beginning, succeedingly outline the status of several
    applications that are nearing practical applications, and then focus on biosensing
    applications, with particular attention to metasurface fluorescence (FL) biosensors,
    because FL detection is a major approach in bioscience and biotechnology. However,
    the contributions to FL detection by metasurface biosensors have not been reviewed
    in an extensive and comprehensive manner. Indeed, the metasurface FL biosensors
    have demonstrated capability of detecting a wide range of biomolecules including
    nucleic acids and proteins, such as antigens and antibodies. Notably, they offer
    enhanced sensitivity assays and reduced assay time when compared to conventional
    commercial assays. We here provide a focused review on the current status and
    future directions of metasurface biosensors.
  description_type: abstract
  lang: und

## Creator

- name: Masanobu Iwanaga
  role: author
  orcid: https://orcid.org/0000-0002-8930-6940
- name: Qi Hu
  role: author
  orcid: https://orcid.org/0000-0003-4315-6665
- name: Youhong Tang
  role: author
  orcid: https://orcid.org/0000-0003-2718-544X

## Contact agent



## Publisher

organization: AIP Publishing

## Managing organization



## Keyword

- subject: Metasurface
  schema: not_defined
- subject: Biosensor
  schema: not_defined
- subject: Fluorescence detection
  schema: not_defined
- subject: DNA
  schema: not_defined
- subject: Antigen
  schema: not_defined
- subject: Antibody
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by-nc-nd/4.0/

## Other identifier(s)



## Data origin



## Embargo



## Journal

- title: Applied Physics Reviews
  issn: '19319401'
  volume: '12'
  issue: '2'

## Conference



## Related item



## Funding

- identifier: JP17H01066
  funder_name: Japan Society for the Promotion of Science
- identifier: JP24K01389
  funder_name: Japan Society for the Promotion of Science

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



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## Fileset

- id: 52239f0e-7bbe-4f25-8c1b-caaa9d71d1bc
  filename: Iwanaga_et_al_ApplPhysRev12(2025)021305.pdf
  content_type: application/pdf
  size: 4827742
  md5: 53011fede031fca2243bc76b26dad670

## Thumbnail

fileset_id: 52239f0e-7bbe-4f25-8c1b-caaa9d71d1bc
filename: Iwanaga_et_al_ApplPhysRev12(2025)021305.pdf