# Macroscopic chiral symmetry breaking in gelation of Fmoc-amino acids: homochiral selective secondary nucleation promoted by the choice of solvent or stirring

https://mdr.nims.go.jp/datasets/c6659d46-86e7-489d-b9ed-a0ad3d6d8dc9

## File

- [MS NR-COM-09-2024-004011 R1.pdf](https://mdr.nims.go.jp/filesets/f0d5eb39-d59b-490d-b500-9265aa9d57be/download) ([Detail](https://mdr.nims.go.jp/filesets/f0d5eb39-d59b-490d-b500-9265aa9d57be.md))

## Id

c6659d46-86e7-489d-b9ed-a0ad3d6d8dc9

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2024-12-06T01:33:51.545348Z

## Updated at

2025-11-03T23:30:10.646204Z

## Published at

2025-11-01T23:22:11.288405Z

## Doi

https://doi.org/10.48505/nims.5110

## First published url

https://doi.org/10.1039/d4nr04011b

## Date published

2024-11-01

## Recorded date published

2024-12-5

## Resource type

journal_article

## Manuscript type

accepted_manuscript

## Collection



## Title

- title: 'Macroscopic chiral symmetry breaking in gelation of Fmoc-amino acids: homochiral
    selective secondary nucleation promoted by the choice of solvent or stirring'
  title_type: original
  lang: en

## Description

- description: A racemic mixture of N-Fmoc-protected phenylalanine or tryptophan was
    found to spontaneously afford a gel enriched in either L- or D-form of their enantiomers
    stochastically.  Homochiral selective secondary nucleation, promoted by the choice
    of solvent or stirring, was suggested as the key process for the observed phenomenon.
  description_type: abstract
  lang: und

## Creator

- name: Kentaro Tashiro
  role: author
  orcid: https://orcid.org/0000-0001-7424-0830

## Contact agent



## Publisher

organization: Royal Society of Chemistry (RSC)

## Managing organization



## Keyword

- subject: Chiral Symmetry Breaking
  schema: not_defined
- subject: Gel
  schema: not_defined
- subject: Secondary Nucleation
  schema: not_defined

## Rights

- identifier: http://rightsstatements.org/vocab/InC/1.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo

start_date: 2024-11-01
end_date: 2025-11-01

## Journal

- title: Nanoscale
  issn: '20403364'
  volume: '16'
  issue: '47'

## Conference



## Related item



## Funding

- identifier: JP23K04844
  funder_name: Japan Society for the Promotion of Science

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: f0d5eb39-d59b-490d-b500-9265aa9d57be
  filename: MS NR-COM-09-2024-004011 R1.pdf
  content_type: application/pdf
  size: 894497
  md5: 207f69bf73734c5feae644cf9d5f44f0

## Thumbnail

fileset_id: f0d5eb39-d59b-490d-b500-9265aa9d57be
filename: MS NR-COM-09-2024-004011 R1.pdf