# Subphthalocyanines as fluorescence sensors for metal cations

https://mdr.nims.go.jp/datasets/b9ff981b-3512-46e4-85a7-a006dcf5ecf6

## File

- [Dalton Trans,2024 - Novakova, Labuta - Subphthalocyanines.pdf](https://mdr.nims.go.jp/filesets/f42c8d9d-a644-4a28-a901-aa2b5485d380/download) ([Detail](https://mdr.nims.go.jp/filesets/f42c8d9d-a644-4a28-a901-aa2b5485d380.md))

## Id

b9ff981b-3512-46e4-85a7-a006dcf5ecf6

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2024-08-09T07:14:00.933465Z

## Updated at

2024-08-19T07:30:34.453652Z

## Published at

2024-08-19T07:30:34.533942Z

## Doi



## First published url

https://doi.org/10.1039/d3dt03839d

## Date published

2024-01-04

## Recorded date published

2024-2-6

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Subphthalocyanines as fluorescence sensors for metal cations
  title_type: original
  lang: en

## Description

- description: Subphthalocyanines (SubPcs) and their aza-analogues (SubTPyzPz) are
    fluorophores with strong orange fluorescence emission, however, their sensing
    ability towards metal cations remains uncharted. To fill this gap, we have developed
    an efficient method for introducing aza-crown moieties at the axial position of
    SubPcs and SubTPyzPzs to investigate the structure-activity relationship for sensing
    of alkali (Li+, Na+, K+) and alkaline earth metal (Ca2+, Mg2+, Ba2+) cations.
    SubPcs showed better photostability than SubTPyzPzs and even commonly utilized
    dye, 6-carboxyfluorescein. Selectivity toward metal cations was driven by the
    size of an aza-crown, irrespective of the counter anion. The stoichiometry of
    binding was found to be 1:1 in all cases, and interaction between SubPcs and cations
    was characterized by corresponding apparent binding constants (Ka). Notably, an
    unusually strong interaction of all sensoric SubPcs with Ba2+ compared to other
    studied cations was demonstrated. The role of surrounding environment, i.e. the
    addition of water or methanol, for sensing cations is shown in detail as well.
    Selectivity towards K+ over Na+ was demonstrated in aqueous media with SubPcs
    bearing 1-aza6-crown-18 moiety in Tween 80 micelles. In this case, a 5-fold increase
    of fluorescence quantum yield was observed upon binding K+ ions. The high brightness,
    photostability, and sensing activity in aqueous media make SubPcs macrocycles
    promising fluorophores for metal cation sensing.
  description_type: abstract
  lang: und

## Creator

- name: Mary Angelia Alfred
  role: author
- name: Kamil Lang
  role: author
- name: Kaplan Kirakci
  role: author
- name: Pavel Stuzhin
  role: author
- name: Petr Zimcik
  role: author
- name: Jan Labuta
  role: author
  orcid: https://orcid.org/0000-0002-8329-0634
  organization: National Institute for Materials Science
  ror: https://ror.org/026v1ze26
- name: Veronika Novakova
  role: author

## Contact agent



## Publisher

organization: Royal Society of Chemistry (RSC)

## Managing organization



## Keyword

- subject: sensing
  schema: not_defined
- subject: metal cations
  schema: not_defined
- subject: host-guest complex
  schema: not_defined
- subject: subphthalocyanine
  schema: not_defined
- subject: fluorescence
  schema: not_defined
- subject: aqueous media
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by-nc/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Dalton Transactions
  issn: '14779234'
  start_page: 2635
  end_page: 2644

## Conference



## Related item



## Funding

- identifier: 21-14919J
  funder_name: Grantová Agentura České Republiky
- identifier: 20-53-26004
  funder_name: Russian Foundation for Basic Research
- identifier: SVV 260 666
  funder_name: Univerzita Karlova v Praze
- identifier: PRIMUS/20/SCI/013
  funder_name: Univerzita Karlova v Praze

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: f42c8d9d-a644-4a28-a901-aa2b5485d380
  filename: Dalton Trans,2024 - Novakova, Labuta - Subphthalocyanines.pdf
  content_type: application/pdf
  size: 1047400
  md5: a177f344a4f9acb80ba6593ed7c03504

## Thumbnail

fileset_id: f42c8d9d-a644-4a28-a901-aa2b5485d380
filename: Dalton Trans,2024 - Novakova, Labuta - Subphthalocyanines.pdf