Article Influences of combined supplementation of calcium citrate and calcium carbonate on injectable and anti-washout hydroxyapatite/collagen bone paste utilizing sodium alginate

Naga Vijaya Lakshmi MANCHINASETTY ; Taira SATO ; Mamoru AIZAWA ; Sridharan MADANAGURUSAMY ; Masanori KIKUCHI SAMURAI ORCID (National Institute for Materials Science)

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Naga Vijaya Lakshmi MANCHINASETTY, Taira SATO, Mamoru AIZAWA, Sridharan MADANAGURUSAMY, Masanori KIKUCHI. Influences of combined supplementation of calcium citrate and calcium carbonate on injectable and anti-washout hydroxyapatite/collagen bone paste utilizing sodium alginate. Journal of the Ceramic Society of Japan. 2017, 125 (7), 579-583.
SAMURAI

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(abstract)

Influences of combined supplementation of calcium citrate (Ca-Cit) and calcium carbonate (CaCO3) on the hydroxyapatite/collagen (HAp/Col) – sodium alginate (Na-Alg) paste (HAp/Col paste) were investigated. Supplementation amounts of Ca-Cit and CaCO3 were denoted as Nx, where N is a multiplication number to Ca2+ ion amounts for the equivalent reaction with Na-Alg obtained previously. Combined supplementation of 10x Ca-Cit and 2x CaCO3 improved the anti-washout property at a washout ratio of 2.42 ± 0.72 % and pH maintenance at 7.34 ± 0.08, these values were better than the best HAp/Col paste using Ca-Cit (5.91 ± 2.73 % washout ratio and 6.72 ± 0.06 of pH). The HAp/Col paste is expected to be utilized in minimally invasive surgery of bone defects.

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Keyword: Composites, Biomedical applications, Hydroxyapatite/collagen composite, Injectable bone paste, Calcium citrate, Sodium alginate

Date published: 2017-06-30

Publisher: Ceramic Society of Japan

Journal:

  • Journal of the Ceramic Society of Japan (ISSN: 18820743) vol. 125 issue. 7 p. 579-583

Funding:

Manuscript type: Publisher's version (Version of record)

MDR DOI:

First published URL: https://doi.org/10.2109/jcersj2.17016

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Updated at: 2024-03-19 16:56:19 +0900

Published on MDR: 2024-03-19 16:56:20 +0900

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