# Formation of hierarchical supramolecular microstructures from 6-                    <i>O</i>                    -alkylated α-cyclodextrin and their application to the selective extraction of long-chain unsaturated fatty acid esters

https://mdr.nims.go.jp/datasets/a6ecc1fa-a022-4429-b8d8-a7837cc5f091

## File

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## Id

a6ecc1fa-a022-4429-b8d8-a7837cc5f091

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2026-08-18T05:49:31.645056Z

## Updated at

2026-08-18T07:41:48.460305Z

## Published at

2026-08-18T09:28:37.425397Z

## Doi



## First published url

https://doi.org/10.1039/d6ra04383f

## Date published

2026-07-06

## Recorded date published

2026-8-5

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: |-
    Formation of hierarchical supramolecular microstructures from 6-
                        <i>O</i>
                        -alkylated α-cyclodextrin and their application to the selective extraction of long-chain unsaturated fatty acid esters
  title_type: original
  lang: en

## Description

- description: We successfully fabricated rhombic plate-like microstructures composed
    of layered assemblies ofhead-tohead supramolecular dimers of 6-O-methylated and
    6-O-ethylated a-cyclodextrins (6-Me-a-CD and 6Et-a-CD, respectively). 6-Me-a-CD
    selectively extracted methyl elaidate (trans) over methyl oleate (cis) in methanol
    via microstructure formation driven by inclusion complexation between the 6-Me-a-CD
    dimer and fatty acid esters, whereas 6-Et-a-CD exhibited the opposite selectivity.
    These results demonstrate that subtle modulation of the alkyl chain length at
    the 6-O position of a-CD enables reversal of cis/trans selectivity in supramolecular
    extraction behavior. The origin of this selectivity was further elucidated by
    theoretical calculations based on density functional theory (DFT) and fragment
    molecular orbital (FMO) interaction energy analysis.
  description_type: abstract
  lang: und

## Creator

- name: Haruya Ishida
  role: author
- name: Shuhei Miyakawa
  role: author
- name: Hajime Shigemitsu
  role: author
  orcid: https://orcid.org/0000-0002-3104-049X
  organization: National Institute for Materials Science
- name: Kaori Fukuzawa
  role: author
- name: Toshiyuki Kida
  role: author

## Contact agent



## Publisher

organization: Royal Society of Chemistry (RSC)

## Managing organization



## Keyword

- subject: Cyclodextrin
  schema: not_defined
- subject: Supramolecular Microstructure
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by-nc/4.0/
  date_licensed: 2026-07-06

## Other identifier(s)



## Data origin



## Embargo



## Journal

- title: RSC Advances
  issn: '20462069'
  volume: '16'
  issue: '36'
  start_page: 38221
  end_page: 38227

## Conference



## Related item



## Funding

- identifier: 22H02146
  funder_name: Japan Society for the Promotion of Science

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



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## Custom property



## Fileset

- id: 619b9844-3cce-4181-98f3-1b83b740bb63
  filename: d6ra04383f.pdf
  content_type: application/pdf
  size: 1163128
  md5: fb610b6c34c23ef7a22ff0ed9cd7b1ea

## Thumbnail

fileset_id: 619b9844-3cce-4181-98f3-1b83b740bb63
filename: d6ra04383f.pdf