# CNC-Milled Superhydrophobic Macroporous Monoliths for 3D Cell Culture

https://mdr.nims.go.jp/datasets/a637e5ea-2b2a-424c-97f9-69e5a5c5eea2

## File

- [AABM2020_postprint.pdf](https://mdr.nims.go.jp/filesets/02575419-8779-4e53-adb6-f046c3fea2f3/download) ([Detail](https://mdr.nims.go.jp/filesets/02575419-8779-4e53-adb6-f046c3fea2f3.md))

## Id

a637e5ea-2b2a-424c-97f9-69e5a5c5eea2

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2024-05-22T07:27:08.800108Z

## Updated at

2024-06-03T07:30:11.376287Z

## Published at

2024-06-03T07:30:11.847022Z

## Doi

https://doi.org/10.48505/nims.4527

## First published url

https://doi.org/10.1021/acsabm.0c00719

## Date published

2020-08-17

## Recorded date published

2020-8-17

## Resource type

journal_article

## Manuscript type

accepted_manuscript

## Collection



## Title

- title: CNC-Milled Superhydrophobic Macroporous Monoliths for 3D Cell Culture
  title_type: original
  lang: en

## Description

- description: ゾル－ゲル法で作製したナノファイバー強化骨格をもつポリメチルシルセスキオキサン多孔体をCNCミリングによりmm以下の精度で加工し、撥水基板を作製した。この材料を利用して三次元培養を行うことで数mm大の球状スフェロイドを高効率で形成できた。
  description_type: abstract
  lang: und
- description: Polymethylsilsesquioxane macroporous monoliths with a nanofiber-reinforced
    framework, fabricated using the sol-gel method, was machined with sub-millimeter
    precision using CNC milling to produce a hydrophobic substrate. The use of this
    material for three-dimensional cell culture enabled the efficient formation of
    spherical spheroids several millimeters in size.
  description_type: abstract
  lang: en

## Creator

- name: Gen Hayase
  role: author
  orcid: https://orcid.org/0000-0003-1970-6129
  organization: National Institute for Materials Science
- name: Daisuke Yoshino
  role: author

## Contact agent



## Publisher

organization: American Chemical Society (ACS)

## Managing organization



## Keyword

- subject: porous monoliths
  schema: not_defined
- subject: sol-gel
  schema: not_defined
- subject: silsesquioxane
  schema: not_defined
- subject: nanofibers
  schema: not_defined
- subject: hydrophobicity
  schema: not_defined
- subject: micromilling
  schema: not_defined
- subject: 3d cell culture
  schema: not_defined

## Rights

- description: This document is the Accepted Manuscript version of a Published Work
    that appeared in final form in ACS Applied Bio Materials, copyright © 2020 American
    Chemical Society after peer review and technical editing by the publisher. To
    access the final edited and published work see https://doi.org/10.1021/acsabm.0c00719
  identifier: http://rightsstatements.org/vocab/InC/1.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo

start_date: 2020-07-21
end_date: 2021-07-21

## Journal

- title: ACS Applied Bio Materials
  issn: '25766422'
  volume: '3'
  issue: '8'
  start_page: 4747
  end_page: 4750

## Conference



## Related item



## Funding

- funder_name: Takeda Science Foundation
- funder_name: Ministry of Education, Culture, Sports, Science and Technology
- identifier: 17K14541
  funder_name: Japan Society for the Promotion of Science

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: '02575419-8779-4e53-adb6-f046c3fea2f3'
  filename: AABM2020_postprint.pdf
  content_type: application/pdf
  size: 686665
  md5: d232f7cb4f31a5411d2612c2ced6d376

## Thumbnail

fileset_id: '02575419-8779-4e53-adb6-f046c3fea2f3'
filename: AABM2020_postprint.pdf