# Fe-electrocatalytic deoxygenative Giese reaction

https://mdr.nims.go.jp/datasets/938e322b-4061-459f-8125-855fa10adacc

## File

- [s41467-025-63515-x-1.pdf](https://mdr.nims.go.jp/filesets/8d275dcf-31ba-48ad-a3a2-7d6b05c64ea0/download) ([Detail](https://mdr.nims.go.jp/filesets/8d275dcf-31ba-48ad-a3a2-7d6b05c64ea0.md))

## Id

938e322b-4061-459f-8125-855fa10adacc

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-12-24T05:13:27.214183Z

## Updated at

2025-12-24T06:09:39.497059Z

## Published at

2025-12-24T07:20:28.595913Z

## Doi



## First published url

https://doi.org/10.1038/s41467-025-63515-x

## Date published

2025-09-26

## Recorded date published



## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Fe-electrocatalytic deoxygenative Giese reaction
  title_type: original
  lang: en

## Description

- description: "A redox-neutral Fe-electrocatalytic deoxygenative Giese reaction is
    reported.\r\nHydroxyl groups are among the most abundant functional groups; therefore,
    the development of efficient methods for their transformation is of significant
    importance in medicinal and process chemistry. Here, we present a redox-neutral
    Giese reaction that proceeds via anodic oxidation to generate phosphonium ions,
    combined with cathodic reduction to furnish low-valent Fe catalysts. This reaction
    represents a promising example of a redox-neutral transformation enabled by an
    Fe catalyst and electrochemistry. The results obtained in this study will facilitate
    the exploration of a broad range of novel reactions employing this redox cycle
    in the future."
  description_type: abstract
  lang: und

## Creator

- name: Longhui Yu
  role: author
- name: Shangzhao Li
  role: author
- name: Hiroshige Ogawa
  role: author
- name: Yilin Ma
  role: author
- name: Qing Chen
  role: author
- name: Ken Yamazaki
  role: author
- name: Yuuya Nagata
  role: author
  orcid: https://orcid.org/0000-0001-5926-5845
  organization: National Institute for Materials Science
- name: Hugh Nakamura
  role: author

## Contact agent



## Publisher

organization: Springer Science and Business Media LLC

## Managing organization



## Keyword

- subject: Fe-electrocatalysis
  schema: not_defined
- subject: Deoxygenative Giese reaction
  schema: not_defined
- subject: Redox-neutral electrochemistry
  schema: not_defined
- subject: C–C bond formation
  schema: not_defined
- subject: Hydroxyl group functionalization
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by-nc-nd/4.0/
  date_licensed: 2025-09-26

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Nature Communications
  issn: '20411723'
  volume: '16'
  issue: '1'
  article_number: '8379'

## Conference



## Related item



## Funding

- identifier: ECS, HKUST 26302024
  funder_name: Research Grants Council, University Grants Committee
- identifier: Start-up funds (Project No. R9820)
  funder_name: Hong Kong University of Science and Technology

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 8d275dcf-31ba-48ad-a3a2-7d6b05c64ea0
  filename: s41467-025-63515-x-1.pdf
  content_type: application/pdf
  size: 1463586
  md5: 5354266d62c944801fff82c3f3d87a82

## Thumbnail

fileset_id: 8d275dcf-31ba-48ad-a3a2-7d6b05c64ea0
filename: s41467-025-63515-x-1.pdf