# How Does Microtubular Network Assists in Determining the Location of Daughter Nucleus: Electromagnetic Resonance as Key to 3D Geometric Engineering

https://mdr.nims.go.jp/datasets/91a71090-1ab9-4ccb-a36b-38a9e73fe7f8

## File

- [Microtubule assembly resonance version 93 September 2018.docx](https://mdr.nims.go.jp/filesets/ab32a7b9-155e-488b-8149-0f4217bf181f/download) ([Detail](https://mdr.nims.go.jp/filesets/ab32a7b9-155e-488b-8149-0f4217bf181f.md))

## Id

91a71090-1ab9-4ccb-a36b-38a9e73fe7f8

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-01-09T02:41:12.757059Z

## Updated at

2025-01-15T07:31:39.222915Z

## Published at

2025-01-15T07:31:39.284977Z

## Doi

https://doi.org/10.48505/nims.5272

## First published url

https://doi.org/10.1007/978-981-99-1916-1_26

## Date published

2023-06-28

## Recorded date published

2023

## Resource type

book_part

## Manuscript type

authors_original

## Collection



## Title

- title: 'How Does Microtubular Network Assists in Determining the Location of Daughter
    Nucleus: Electromagnetic Resonance as Key to 3D Geometric Engineering'
  title_type: original
  lang: en

## Description

- description: "A dividing cell finds precisely the future 3D location to put its
    daughter cell by sensing the environment far outside its cell boundary. Making
    such a decision begins at a sub-molecular level of a pair of centrioles, eventually
    regulating the intricate geometries of a large life form. Thus far, optical imaging
    and molecular expression delivered little information. Here using theory and experiment,
    we propose that a scanning dielectric microscope (SDM) may predict the direction
    where parents would put their daughter with 65% (SD ± 5%) accuracy. The positioning
    mechanism of a microtubule organization center was monitored live using SDM of
    the 3D matrices of the hippocampal neuron and a HeLa cell network. We theoretically
    analyzed electric and magnetic field distributions at resonance for the relative
    3D orientation of a pair of centrioles within a cell and also centrioles of the
    neighboring cells, beyond the optical range. Then microwave imaging revealed that
    all neighboring cell-centrosomes form a network of coupled vibrations that decides
    the left–right symmetry, symmetric, and asymmetric cell division. Together with
    Maxwell’s equation solver, SDM delivers deep insight into the multi-channel signal
    transmission in biomaterials beyond the optical microscope. For the first time,
    we combined two widely varied physical characterization tools to understand intelligence
    in biological systems.\r\n\r\n"
  description_type: abstract
  lang: und

## Creator

- name: Pushpendra Singh
  role: author
- name: Komal Saxena
  role: author
- name: Parama Dey
  role: author
- name: Pathik Sahoo
  role: author
- name: Kanad Ray
  role: author
- name: Anirban Bandyopadhyay
  role: author
  orcid: https://orcid.org/0000-0002-8823-4914

## Contact agent



## Publisher

organization: Springer Nature Singapore

## Managing organization



## Keyword

- subject: Microtubule network
  schema: not_defined
- subject: cell division
  schema: not_defined
- subject: centriole
  schema: not_defined
- subject: centrosome
  schema: not_defined
- subject: sperm
  schema: not_defined

## Rights

- identifier: http://rightsstatements.org/vocab/InC/1.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Lecture Notes in Networks and Systems
  issn: '23673370'
  start_page: 345
  end_page: 371

## Conference



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## Instrument



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## Measurement method



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## Fileset

- id: ab32a7b9-155e-488b-8149-0f4217bf181f
  filename: Microtubule assembly resonance version 93 September 2018.docx
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  size: 2799125
  md5: 40f76fb82f4034c7671f517089e0f9da

## Thumbnail

fileset_id: ab32a7b9-155e-488b-8149-0f4217bf181f
filename: Microtubule assembly resonance version 93 September 2018.docx