# Cationic Polymer Brushes Functionalized with Carbon Dots and Boronic Acids for Bacterial Detection and Inactivation

https://mdr.nims.go.jp/datasets/90f883bf-bc73-4e82-bd63-4bc8c40b040f

## File

- [zhang-et-al-2025-cationic-polymer-brushes-functionalized-with-carbon-dots-and-boronic-acids-for-bacterial-detection-and.pdf](https://mdr.nims.go.jp/filesets/6dd71ff4-1d5d-4526-ace8-27197e528ff7/download) ([Detail](https://mdr.nims.go.jp/filesets/6dd71ff4-1d5d-4526-ace8-27197e528ff7.md))

## Id

90f883bf-bc73-4e82-bd63-4bc8c40b040f

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-11-13T02:58:40.334298Z

## Updated at

2025-11-13T07:30:20.411030Z

## Published at

2025-11-13T07:24:28.767793Z

## Doi



## First published url

https://doi.org/10.1021/acsomega.5c01507

## Date published

2025-04-15

## Recorded date published

2025-4-15

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Cationic Polymer Brushes Functionalized with Carbon Dots and Boronic Acids
    for Bacterial Detection and Inactivation
  title_type: original
  lang: en

## Description

- description: Drug-resistant bacterial infections are among the most severe physiological
    challenges facing human health. Therefore, the detection and inactivation of pathogenic
    bacteria remains a crucial therapeutic goal in modern society. In this study,
    we design multifunctional nanocomposites aimed at bacterial binding, fluorescence
    labeling, and synergistic antibacterial treatment. These nanocomposites are prepared
    by introducing cationic polymers with quaternary ammonium compounds onto silica
    nanoparticles using surface-initiated atom transfer radical polymerization, followed
    by incorporation of copper-doped carbon dots and modification of boronic acid.
    The cationic polymer units and boronic acid end groups enhance the bacterial binding
    capacity and synergistic bactericidal effects in cooperation with the carbon dots.
    Due to the stable fluorescent properties of carbon dots, the nanocomposites can
    generate fluorescence signals around bacteria, enabling bacterial fluorescence
    imaging. Overall, this study demonstrates a multifunctional nanocomposite-assisted
    strategy for bacterial labeling, imaging, and deactivation, providing a novel
    approach for bacterial detection and synergistic treatment.
  description_type: abstract
  lang: und

## Creator

- name: Qicheng Zhang
  role: author
- name: Si Chen
  role: author
- name: Xiaoting Xue
  role: author
- name: Solmaz Hajizadeh
  role: author
  orcid: https://orcid.org/0000-0002-0348-8756
- name: Tomohiko Yamazaki
  role: author
  orcid: https://orcid.org/0000-0003-2136-8042
- name: Lei Ye
  role: author
  orcid: https://orcid.org/0000-0002-3646-4072

## Contact agent



## Publisher

organization: American Chemical Society (ACS)

## Managing organization



## Keyword

- subject: Polymer brushe
  schema: not_defined
- subject: Carbon dot
  schema: not_defined
- subject: Boronic acid
  schema: not_defined
- subject: bacterial infection
  schema: not_defined
- subject: atom transfer radical polymerization
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin



## Embargo



## Journal

- title: ACS Omega
  issn: '24701343'
  volume: '10'
  issue: '14'
  start_page: 14536
  end_page: 14546

## Conference



## Related item



## Funding

- identifier: 2019-04228
  funder_name: Swedish Research Council VR
- funder_name: Royal Physiographic Society

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 6dd71ff4-1d5d-4526-ace8-27197e528ff7
  filename: zhang-et-al-2025-cationic-polymer-brushes-functionalized-with-carbon-dots-and-boronic-acids-for-bacterial-detection-and.pdf
  content_type: application/pdf
  size: 2983126
  md5: 17f95f9b2122a0da0143cc8b6c8a8f70

## Thumbnail

fileset_id: 6dd71ff4-1d5d-4526-ace8-27197e528ff7
filename: zhang-et-al-2025-cationic-polymer-brushes-functionalized-with-carbon-dots-and-boronic-acids-for-bacterial-detection-and.pdf