# Polydopamine-Coating Nanoarchitectonics of Cellulose Hydrogels with Promoted Sustainable and Alkali-Resistant Natures for 3D Cell Culture Application

https://mdr.nims.go.jp/datasets/8c4aa70f-51a5-47d3-b708-bb6305b5f8a3

## File

- [am-2025-14529h.R2_Author Final.pdf](https://mdr.nims.go.jp/filesets/70a71fb0-8394-4f65-9d67-c200353896a8/download) ([Detail](https://mdr.nims.go.jp/filesets/70a71fb0-8394-4f65-9d67-c200353896a8.md))

## Id

8c4aa70f-51a5-47d3-b708-bb6305b5f8a3

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-09-19T10:30:59.638280Z

## Updated at

2025-09-22T00:14:41.616312Z

## Published at

2026-09-03T23:25:04.824176Z

## Doi

https://doi.org/10.48505/nims.5772

## First published url

https://doi.org/10.1021/acsami.5c14529

## Date published

2025-09-17

## Recorded date published

2025-9-17

## Resource type

journal_article

## Manuscript type

accepted_manuscript

## Collection



## Title

- title: Polydopamine-Coating Nanoarchitectonics of Cellulose Hydrogels with Promoted
    Sustainable and Alkali-Resistant Natures for 3D Cell Culture Application
  title_type: original
  lang: en

## Description

- description: We present a simple and scalable physical treatment strategy to fabricate
    alkali-resistant, physically crosslinked hydrogels from carboxymethyl cellulose
    nanofibers. By combining freeze-drying with mild thermal annealing (70 °C), the
    hydrogel network undergoes partial dehydration and ester bond formation via mild
    thermal condensation between carboxyl and hydroxyl groups, resulting in enhanced
    internal densification while preserving porosity and rehydration capacity.
  description_type: abstract
  lang: und

## Creator

- name: Yurina Sekine
  role: author
  orcid: https://orcid.org/0000-0002-8971-2498
- name: Michiyo Honda
  role: author
- name: Asako Sugita
  role: author
- name: Takuya Nankawa
  role: author
  orcid: https://orcid.org/0000-0002-2889-1242
- name: Rimi Sakanaka
  role: author
- name: Tomoko Ikeda-Fukazawa
  role: author
- name: Katsuhiko Ariga
  role: author
  orcid: https://orcid.org/0000-0002-2445-2955

## Contact agent



## Publisher

organization: American Chemical Society (ACS)

## Managing organization



## Keyword

- subject: carboxymethyl cellulose nanofibers
  schema: not_defined
- subject: hydrogel stability
  schema: not_defined
- subject: freeze-drying
  schema: not_defined
- subject: heat treatment
  schema: not_defined
- subject: polydopamine coating
  schema: not_defined
- subject: 3D cell culture
  schema: not_defined

## Rights

- description: This document is the Accepted Manuscript version of a Published Work
    that appeared in final form in ACS Applied Materials & Interfaces, copyright ©
    2025 American Chemical Society after peer review and technical editing by the
    publisher. To access the final edited and published work see https://doi.org/10.1021/acsami.5c14529.
  identifier: http://rightsstatements.org/vocab/InC/1.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo

start_date: 2025-09-04
end_date: 2026-09-04

## Journal

- title: ACS Applied Materials & Interfaces
  issn: '19448244'
  volume: '17'
  issue: '37'
  start_page: 52768
  end_page: 52778

## Conference



## Related item



## Funding

- identifier: 23K20875
  funder_name: Japan Society for the Promotion of Science
- identifier: 24K01409
  funder_name: Japan Society for the Promotion of Science
- identifier: 24K10550
  funder_name: Japan Society for the Promotion of Science

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 70a71fb0-8394-4f65-9d67-c200353896a8
  filename: am-2025-14529h.R2_Author Final.pdf
  content_type: application/pdf
  size: 1306293
  md5: b9729fe64a8bec5d5c421667df1cb14e

## Thumbnail

fileset_id: 70a71fb0-8394-4f65-9d67-c200353896a8
filename: am-2025-14529h.R2_Author Final.pdf