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説明:

We present a simple and scalable physical treatment strategy to fabricate alkali-resistant, physically crosslinked hydrogels from carboxymethyl cellulose nanofibers. By combining freeze-drying with mild thermal annealing (70 °C), the hydrogel network undergoes partial dehydration and ester bond formation via mild thermal condensation between carboxyl and hydroxyl groups, resulting in enhanced internal densification while preserving porosity and rehydration capacity.

権利情報:

• In Copyright
  

  This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Applied Materials & Interfaces, copyright © 2025 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acsami.5c14529.

キーワード: carboxymethyl cellulose nanofibers, hydrogel stability, freeze-drying, heat treatment, polydopamine coating, 3D cell culture

刊行年月日: 2025-09-17

出版者: American Chemical Society (ACS)

掲載誌:

• ACS Applied Materials & Interfaces (ISSN: 19448244) vol. 17 issue. 37 p. 52768-52778

研究助成金:

• Japan Society for the Promotion of Science 23K20875
• Japan Society for the Promotion of Science 24K01409
• Japan Society for the Promotion of Science 24K10550

原稿種別: 著者最終稿 (Accepted manuscript)

MDR DOI: https://doi.org/10.48505/nims.5772

公開URL: https://doi.org/10.1021/acsami.5c14529

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更新時刻: 2025-09-22 09:14:41 +0900

MDRでの公開時刻: 2026-09-04 08:25:04 +0900