# Research Strategies and Methods of Hydrogels for Antitumor Drug Delivery

https://mdr.nims.go.jp/datasets/8be9b5d3-4d2a-4cae-8142-157c0bc96a63

## File

- [biomedicines-13-01899-v2.pdf](https://mdr.nims.go.jp/filesets/216a8fd2-3384-4fc1-914a-595df533a8c8/download) ([Detail](https://mdr.nims.go.jp/filesets/216a8fd2-3384-4fc1-914a-595df533a8c8.md))

## Id

8be9b5d3-4d2a-4cae-8142-157c0bc96a63

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-09-02T01:26:25.127339Z

## Updated at

2025-09-02T07:30:25.186216Z

## Published at

2025-09-02T03:24:59.385007Z

## Doi



## First published url

https://doi.org/10.3390/biomedicines13081899

## Date published

2025-08-04

## Recorded date published



## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Research Strategies and Methods of Hydrogels for Antitumor Drug Delivery
  title_type: original
  lang: en

## Description

- description: Tumor treatments have substantially advanced through various approaches,
    including chemotherapy, radiotherapy, immunotherapy, and gene therapy. However,
    efficient treatment necessitates overcoming physiological barriers that impede
    the delivery of therapeutic agents to target sites. Drug delivery systems (DDSs)
    are a prominent research area, particularly in tumor therapy. This review provides
    a comprehensive overview of hydrogel-based DDSs for tumor treatment, focusing
    on the strategies and designs of DDSs based on the unique pathophysiological characteristics
    of tumors. The design and preparation of hydrogel systems for DDSs are summarized
    and highlighted. The challenges and opportunities for translating hydrogel-based
    DDSs into clinical applications are discussed.
  description_type: abstract
  lang: und

## Creator

- name: Tianjiao Zeng
  role: author
  orcid: https://orcid.org/0000-0002-1286-0337
- name: Lusi Chen
  role: author
- name: Toru Yoshitomi
  role: author
  orcid: https://orcid.org/0000-0003-3847-1812
- name: Naoki Kawazoe
  role: author
  orcid: https://orcid.org/0000-0003-3916-0709
- name: Yingnan Yang
  role: author
- name: Guoping Chen
  role: author
  orcid: https://orcid.org/0000-0001-6753-3678

## Contact agent



## Publisher

organization: MDPI AG

## Managing organization



## Keyword

- subject: hydrogel
  schema: not_defined
- subject: drug delivery system
  schema: not_defined
- subject: " antitumor therapy"
  schema: not_defined
- subject: combination therapy
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Biomedicines
  issn: '22279059'
  volume: '13'
  issue: '8'
  article_number: '1899'

## Conference



## Related item



## Funding

- identifier: 19H04475
  funder_name: JSPS KAKENHI
- identifier: 24K03289
  funder_name: JSPS KAKENHI

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 216a8fd2-3384-4fc1-914a-595df533a8c8
  filename: biomedicines-13-01899-v2.pdf
  content_type: application/pdf
  size: 1635944
  md5: eea69d2843b6576faa22a4447b0802b9

## Thumbnail

fileset_id: 216a8fd2-3384-4fc1-914a-595df533a8c8
filename: biomedicines-13-01899-v2.pdf