Suhyeon Kim
;
Seongmin Ga
;
Hayeon Bae
;
Ronald Sluyter
;
Konstantin Konstantinov
;
Lok Kumar Shrestha
(National Institute for Materials Science)
;
Yong Ho Kim
;
Jung Ho Kim
;
Katsuhiko Ariga
(National Institute for Materials Science)
説明:
(abstract)Enzyme biocatalysis is reshaping pharmaceutical synthesis, offering sustainable and efficient pathways for drug discovery and production. This paradigm shift towards eco-friendly methodologies addresses concerns inherent in traditional chemical synthesis. Enzymes, celebrated for their precision and adaptability to mild conditions, are poised as ideal candidates for pharmaceutical applications. Their versatility facilitates the synthesis of diverse pharmaceutical compounds, ensuring precise drug design and minimizing environmental impact. The integration of multidisciplinary approaches, including protein engineering, computational biology, and nanoarchitectonics, holds the potential to propel enzyme biocatalysis even further. Protein engineering utilizes directed evolution and rational design to customize enzymes, enhancing their stability and efficacy.
権利情報:
キーワード: enzyme, biocatalysis, protein
刊行年月日: 2023-10-28
出版者: Royal Society of Chemistry (RSC)
掲載誌:
研究助成金:
原稿種別: 出版者版 (Version of record)
MDR DOI:
公開URL: https://doi.org/10.1039/d3ey00239j
関連資料:
その他の識別子:
連絡先:
更新時刻: 2024-01-18 16:57:46 +0900
MDRでの公開時刻: 2024-01-19 08:30:14 +0900
| ファイル名 | サイズ | |||
|---|---|---|---|---|
| ファイル名 |
EESCatal24_2_14.pdf
(サムネイル)
application/pdf |
サイズ | 8.52MB | 詳細 |