Chemical characterization of Corydalis chaerophylla D.C. extracts and preliminary evaluation of their in vitro and in vivo biological properties

Binita Maharjan; Lok Kumar Shrestha; Jonathan P. Hill; Katsuhiko Ariga; Shyam Sharan Shrestha; Stefania Sut; Ram Lal Swagat Shrestha; Stefano Dall’Acqua

Article Chemical characterization of Corydalis chaerophylla D.C. extracts and preliminary evaluation of their in vitro and in vivo biological properties

Binita Maharjan (Tribhuvan University) ; Lok Kumar Shrestha (National Institute for Materials Science) ; Jonathan P. Hill (National Institute for Materials Science) ; Katsuhiko Ariga (National Institute for Materials Science) ; Shyam Sharan Shrestha (Himalayan Research and Development Center) ; Stefania Sut (University of Padova) ; Ram Lal Swagat Shrestha (Tribhuvan University) ; Stefano Dall’Acqua (University of Padova)

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Binita Maharjan, Lok Kumar Shrestha, Jonathan P. Hill, Katsuhiko Ariga, Shyam Sharan Shrestha, Stefania Sut, Ram Lal Swagat Shrestha, Stefano Dall’Acqua. Chemical characterization of Corydalis chaerophylla D.C. extracts and preliminary evaluation of their in vitro and in vivo biological properties. CHEMISTRY & BIODIVERSITY. 2023, 20 (12), e202301209.

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Genus Corydalis is a rich source of isoquinoline alkaloids having potential bioactivities. Corydalis chaerophylla collected from Nepal at an altitude of 2400 - 4800 m was extracted using hexane, methanol and chloroform as solvents. The resulting hexane, methanol and chloroform extracts were subjected to LC-DAD-MS analysis for identification of the fifteen different alkaloids present on the basis of reference standards and fragmentation patterns.

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