Chemical characterization of Corydalis chaerophylla D.C. extracts and preliminary evaluation of their in vitro and in vivo biological properties

Binita Maharjan; Lok Kumar Shrestha; Jonathan P. Hill; Katsuhiko Ariga; Shyam Sharan Shrestha; Stefania Sut; Ram Lal Swagat Shrestha; Stefano Dall’Acqua

doi:10.1002/cbdv.202301209

Journal article Chemical characterization of Corydalis chaerophylla D.C. extracts and preliminary evaluation of their in vitro and in vivo biological properties

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Binita Maharjan, Lok Kumar Shrestha, Jonathan P. Hill, Katsuhiko Ariga, Shyam Sharan Shrestha, Stefania Sut, Ram Lal Swagat Shrestha, Stefano Dall’Acqua. Chemical characterization of Corydalis chaerophylla D.C. extracts and preliminary evaluation of their in vitro and in vivo biological properties. CHEMISTRY & BIODIVERSITY. 2023, 20 (12), e202301209. https://doi.org/10.1002/cbdv.202301209

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Genus Corydalis is a rich source of isoquinoline alkaloids having potential bioactivities. Corydalis chaerophylla collected from Nepal at an altitude of 2400 - 4800 m was extracted using hexane, methanol and chloroform as solvents. The resulting hexane, methanol and chloroform extracts were subjected to LC-DAD-MS analysis for identification of the fifteen different alkaloids present on the basis of reference standards and fragmentation patterns.

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