# Layer-by-layer assembled film can serve as an enhanced reaction environment for Diels–Alder reaction

https://mdr.nims.go.jp/datasets/7a1edf31-9184-4729-980a-30f3e1a4222c

## Files

- [fchem-12-1524096 (1).pdf](https://mdr.nims.go.jp/filesets/45c8a883-980a-45ed-959e-a8b33af6e6a4/download) ([Detail](https://mdr.nims.go.jp/filesets/45c8a883-980a-45ed-959e-a8b33af6e6a4.md))

## Id

7a1edf31-9184-4729-980a-30f3e1a4222c

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2024-12-16T07:11:06.954671Z

## Updated at

2024-12-17T23:30:41.959345Z

## Published at

2024-12-17T23:30:42.038154Z

## Doi



## First published url

https://doi.org/10.3389/fchem.2024.1524096

## Date published

2024-12-12

## Recorded date published



## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Layer-by-layer assembled film can serve as an enhanced reaction environment
    for Diels–Alder reaction
  title_type: original
  lang: en

## Description

- description: Although the Diels–Alder reaction (DA) has garnered significant attention
    due to its numerous advantages, its long reaction time is a drawback. Herein,
    we investigated the effects of polarity difference on DA using Layer-by-Layer
    (LbL) films comprising polycationic polyallylamine hydrochloride and polyanionic
    poly (styrenesulfonic acid-co-furfuryl methacrylate) [poly (SS-co-FMA)] as the
    reaction environment. First, furan composition in poly (SS-co-FMA) was adjusted
    to be 19 mol% to achieve good water solubility and layer deposition. The successful
    formation of LbL films with 8 and 40 layers was confirmed by quartz crystal microbalance.
    The polarity within films and, consequently, the DA efficiency between furfuryl
    methacrylate and the maleimide in MAL-PEG2-NHS increased with an increasing number
    of layers up to 40 layers without requiring chemical modification on the reaction
    site of DA or any catalysts. Furthermore, we employed the LbL coating on the surface
    of magnetic nanoparticles (MNPs). The retro DA reaction (rDA) was successfully
    triggered by heating the MNPs by AC magnetic field. We believe that the proposed
    technology can serve as an enhanced DA reaction environment as well as temporal/spatial
    control of rDA in various applications.
  description_type: abstract
  lang: und

## Creator

- name: Nanami Fujisawa
  role: author
  orcid: https://orcid.org/0000-0002-8894-1790
  organization: National Institute for Materials Science
  ror: https://ror.org/026v1ze26
- name: Mitsuhiro Ebara
  role: author
  orcid: https://orcid.org/0000-0002-7906-0350
  organization: National Institute for Materials Science
  ror: https://ror.org/026v1ze26

## Contact agent



## Publisher

organization: Frontiers Media SA

## Managing organization



## Keyword

- subject: Diels-Alder reaction
  schema: not_defined
- subject: layer-by-layer
  schema: not_defined
- subject: quartz crystal microbalance
  schema: not_defined
- subject: magnetic nanoparticles
  schema: not_defined
- subject: AC magnetic field
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Frontiers in Chemistry
  issn: '22962646'
  volume: '12'
  article_number: '1524096'

## Conference



## Related item



## Funding



## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 45c8a883-980a-45ed-959e-a8b33af6e6a4
  filename: fchem-12-1524096 (1).pdf
  content_type: application/pdf
  size: 1548202
  md5: 2cca67f21f4cb78ab85e6ccb8647d15e

## Thumbnail

fileset_id: 45c8a883-980a-45ed-959e-a8b33af6e6a4
filename: fchem-12-1524096 (1).pdf