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Electrospun fiber mat with an average diameter = 1.5 μm, having initiating groups for surface-initiated atom transfer radical polymerization (SI-ATRP) was prepared using a random copolymer of styrene (ST) and 4-vinylbenzyl 2-bromopropionate (VBP). Then, SI-ATRP of hydrophilic styrene sodium sulfonate (SSNa) was carried out on the fiber mat, yielding high-dense graft layer on the fiber (the graft density was about 0.2 chains/nm2). The short fiber with an average length = 30 - 150 μm was obtained by mechanical cutting. We cultured chicken embryonic keratocyte cells with the short fibers for prescribe time. SEM observation confirmed self-aggregation of the cells and the short fibers. Histological analysis revealed that cells homogenously existed inside the aggregates and the cell viability was high (~ 80%).

権利情報:

• In Copyright
  

キーワード: Electrospining, Concentrated polymer brushes, Cells, short fibers, Self-assembly

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会議: Biomaterials International 2026 (2026-07-26 - 2026-07-30)

研究助成金:

• JSPS 19KK0368, 22H02133 and 24KF0166

原稿種別: 論文以外のデータ

MDR DOI: https://doi.org/10.48505/nims.6520

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更新時刻: 2026-09-15 09:28:11 +0900

MDRでの公開時刻: 2026-09-15 10:27:22 +0900