# Comparative Degradation Behavior of Carbonate Apatite-Coated and Hydroxyapatite-Coated Mg-Ca Alloy Plates and Screws in Rabbit Femurs

https://mdr.nims.go.jp/datasets/65d91b23-28e3-4a50-8128-fd72627e9e89

## Files

- [MDR用 Comparative Degradation Behavior of Carbonate Apatite‑Coated and.pdf](https://mdr.nims.go.jp/filesets/102b8c2c-6ae7-40d2-885e-27cc0b4a118f/download) ([Detail](https://mdr.nims.go.jp/filesets/102b8c2c-6ae7-40d2-885e-27cc0b4a118f.md))

## Id

65d91b23-28e3-4a50-8128-fd72627e9e89

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-08-26T05:00:44.879161Z

## Updated at

2025-08-27T03:30:23.065328Z

## Published at

2025-08-26T23:19:16.417712Z

## Doi

https://doi.org/10.48505/nims.5674

## First published url

https://doi.org/10.1007/s44174-024-00217-w

## Date published

2024-08-02

## Recorded date published

2025-9

## Resource type

journal_article

## Manuscript type

accepted_manuscript

## Collection



## Title

- title: Comparative Degradation Behavior of Carbonate Apatite-Coated and Hydroxyapatite-Coated
    Mg-Ca Alloy Plates and Screws in Rabbit Femurs
  title_type: original
  lang: en

## Description

- description: Carbonate apatite (CAp) and hydroxyapatite (HAp) coatings have been
    developed as bioabsorbable and non-absorbable corrosion suppression coatings,
    respectively, for biodegradable Mg alloys. In this study, CAp and HAp coatings
    were formed on Mg-0.8mass% Ca (MgCa) alloy plates and screws and implanted in
    rabbit femurs with uncoated devices for 2 and 6 months. Cross section of the retrieved
    devices was observed using scanning electron microscope to observe the details.
    The CAp and HAp coatings suppressed apparent corrosion of MgCa devices for 2 months.
    The CAp coating suppressed subsequent corrosion to show only several micro corrosion
    pits. The cross-sectional reduction of the CAp-coated plates and screws at 6 months
    was about 20% and 50% of that of the uncoated devices, respectively. The corrosion
    of the HAp-coated devices progressed locally to show millimeter-sized pits at
    6 months, and their cross-sectional reduction was around 50% of that of the uncoated
    devices. The CAp coating began to disintegrate between 2 and 6 months preferentially
    in area with new bone formation, while the HAp coating almost remained the original
    shape. It was shown that the CAp coating can suppress the corrosion of MgCa and
    be absorbed by new bone.
  description_type: abstract
  lang: und

## Creator

- name: Sachiko Hiromoto
  role: author
  orcid: https://orcid.org/0000-0003-4666-6708
- name: Etsuro Nozoe
  role: author
- name: Kotaro Hanada
  role: author
- name: Takuya Yoshimura
  role: author
- name: Kaori Shima
  role: author
- name: Norifumi Nakamura
  role: author
- name: Aya Chiba
  role: author

## Contact agent



## Publisher

organization: Springer Science and Business Media LLC

## Managing organization



## Keyword

- subject: Bioabsorbable carbonate apatite coating
  schema: not_defined
- subject: biodegradable magnesium alloy
  schema: not_defined
- subject: in vivo
  schema: not_defined
- subject: biomaterials
  schema: not_defined

## Rights

- description: 'This version of the article has been accepted for publication, after
    peer review (when applicable) and is subject to Springer Nature’s AM terms of
    use, but is not the Version of Record and does not reflect post-acceptance improvements,
    or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s44174-024-00217-w.'
  identifier: http://rightsstatements.org/vocab/InC/1.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo

start_date: 2024-08-02
end_date: 2025-08-02

## Journal

- title: Biomedical Materials & Devices
  issn: '27314812'
  volume: '3'
  issue: '2'
  start_page: 1183
  end_page: 1199

## Conference



## Related item



## Funding

- identifier: 20K10012
  funder_name: Japan Society for the Promotion of Science
- identifier: 22H01798
  funder_name: Japan Society for the Promotion of Science

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 102b8c2c-6ae7-40d2-885e-27cc0b4a118f
  filename: MDR用 Comparative Degradation Behavior of Carbonate Apatite‑Coated and.pdf
  content_type: application/pdf
  size: 8884217
  md5: b80631405fb580a361ddf80398799465

## Thumbnail

fileset_id: 102b8c2c-6ae7-40d2-885e-27cc0b4a118f
filename: MDR用 Comparative Degradation Behavior of Carbonate Apatite‑Coated and.pdf