# Use of an Ion-exchange Adduct of Synthetic Hectorite and Chiral Copper(II) Complex as a Packing Material for Chromatographic Resolution

https://mdr.nims.go.jp/datasets/41d8bf31-25f7-42b5-8af9-62cd2f78c955

## File

- [2024_ApplClaySci_Packing material for HPLC（MDR）.pdf](https://mdr.nims.go.jp/filesets/6ceb64b3-2806-4c2e-b865-be25c83802bf/download) ([Detail](https://mdr.nims.go.jp/filesets/6ceb64b3-2806-4c2e-b865-be25c83802bf.md))

## Id

41d8bf31-25f7-42b5-8af9-62cd2f78c955

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2024-02-21T02:03:16.323803Z

## Updated at

2026-02-20T03:31:00.421888Z

## Published at

2026-02-20T01:23:04.537931Z

## Doi

https://doi.org/10.48505/nims.4410

## First published url

https://doi.org/10.1016/j.clay.2024.107290

## Date published

2024-02-20

## Recorded date published

2024-4

## Resource type

journal_article

## Manuscript type

accepted_manuscript

## Collection



## Title

- title: Use of an Ion-exchange Adduct of Synthetic Hectorite and Chiral Copper(II)
    Complex as a Packing Material for Chromatographic Resolution
  title_type: original
  lang: en

## Description

- description: A spherically shaped particle of synthetic hectorite (denoted as Na-HEC)
    was ion-exchanged with a divalent Cu(II) complex, [Cu(SS-oxa)]2+ (SS-oxa = SS-2,2′-isopropylidene-bis(4-phenyl-2-oxazoline)).
    The material is denoted as [Cu(SS-oxa)]2+/HEC. A column for high performance liquid
    chromatography (HPLC) was prepared by packing 4.0 g of [Cu(SS-oxa)]2+/HEC into
    a stainless tube (25 cm x 0.4 cm (i.d.)). When tris(acetylacetonato)cobalt(III)
    (denoted as [Co(acac)3]) was eluted by methanol at the flow rate of 0.2 mLmin-1
    and 4 oC, the compound was separated to Δ- and Λ-enantiomers nearly to the baseline
    separation. Organic molecules with two hydroxyl groups such as 1,1’-binaphthyl-2,2’-diol
    were also resolved partially. The results promised the practical utility of the
    clay column chromatography for obtaining enantiomeric compounds.
  description_type: abstract
  lang: eng

## Creator

- name: Akihiko Yamagishi
  role: author
  organization: Toho University
- name: Kenji Tamura
  role: author
  orcid: https://orcid.org/0000-0001-6578-0923
  organization: National Institute for Materials Science
  department: Research Center for Electronic and Optical Materials/Functional Materials
    Field/Environmental Circulation Composite Materials Group
  ror: https://ror.org/026v1ze26
- name: Masumi Kamon
  role: author
  organization: National Institute for Materials Science
  department: Research Center for Electronic and Optical Materials/Functional Materials
    Field/Environmental Circulation Composite Materials Group
  ror: https://ror.org/026v1ze26
- name: Jun Yoshida
  role: author
  organization: Nihon University
- name: Hisako Sato
  role: author
  organization: Ehime University

## Contact agent



## Publisher

organization: Elsevier

## Managing organization



## Keyword

- subject: Ion-exchange adducts
  schema: not_defined
- subject: Synthetic hectorite
  schema: not_defined
- subject: Chiral copper(II) complexes
  schema: not_defined
- subject: High performance liquid chromatograph
  schema: not_defined
- subject: Optical resolution
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by-nc-nd/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo

start_date: 2024-02-20
end_date: 2026-02-20

## Journal

- title: APPLIED CLAY SCIENCE
  issn: '01691317'
  volume: '251'
  article_number: '107290'

## Conference



## Related item



## Funding



## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 6ceb64b3-2806-4c2e-b865-be25c83802bf
  filename: 2024_ApplClaySci_Packing material for HPLC（MDR）.pdf
  content_type: application/pdf
  size: 1438678
  md5: 15e78e3ba312bdbfad567f0897c32984

## Thumbnail

fileset_id: 6ceb64b3-2806-4c2e-b865-be25c83802bf
filename: 2024_ApplClaySci_Packing material for HPLC（MDR）.pdf