# Preparation of anti-decay self-setting pastes of hydroxyapatite/collagen utilizing (3-glycidoxypropyl)trimethoxysilane

https://mdr.nims.go.jp/datasets/40566415-4d9d-4ff1-9004-bc0d4a873ceb

## File

- [Preparation of anti decay self setting pastes of hydroxyapatite collagen utilizing 3 glycidoxypropyl trimethoxysilane.pdf](https://mdr.nims.go.jp/filesets/15762ebd-59f3-4049-8f89-34987eabad70/download) ([Detail](https://mdr.nims.go.jp/filesets/15762ebd-59f3-4049-8f89-34987eabad70.md))

## Id

40566415-4d9d-4ff1-9004-bc0d4a873ceb

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2024-03-06T00:52:58.567069Z

## Updated at

2024-03-19T07:56:01.276180Z

## Published at

2024-03-19T07:56:01.680805Z

## Doi



## First published url

https://doi.org/10.1080/21870764.2018.1517712

## Date published

2018-10-02

## Recorded date published

2018-10-2

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Preparation of anti-decay self-setting pastes of hydroxyapatite/collagen
    utilizing (3-glycidoxypropyl)trimethoxysilane
  title_type: original
  lang: en

## Description

- description: This article describes preparation of anti-decay self-setting pastes
    of hydroxyapatite/collagen (HAp/Col) utilizing (3-glycidoxypropyl)trimethoxysilane
    (GPTMS). The powder portion of the paste was ball-milled HAp/Col synthesized by
    the simultaneous titration method, and the liquid portion was GPTMS aqueous solution
    at a concentration of 0.1, 1.0 or 10 % in volume.  The HAp/Col-GPTMS pastes were
    prepared by mixing the powder and liquid portions at powder/liquid (P/L) ratios
    ranging from 0.20 to 2.00 (g/cm3). The pastes with P/L ratios from 0.33 to 1.50
    showed good handling properties, and their viscosities depended greatly on the
    P/L ratio. An animal test using porcine tibia demonstrated no harmful systemic
    or local symptoms, because the GPTMS concentration maintained acceptable levels
    for living tissues through dispersion with body fluid. The animal test also revealed
    that the paste was completely resorbed and substituted with newly formed bone
    after 12 weeks implantation.
  description_type: abstract
  lang: und

## Creator

- name: Taira Sato
  role: author
- name: Yuki Shirosaki
  role: author
- name: Masaki Nagaya
  role: author
- name: Yoshinori Asano
  role: author
- name: Kazuaki Nakano
  role: author
- name: Hiroshi Nagashima
  role: author
- name: Mamoru Aizawa
  role: author
- name: Masanori Kikuchi
  role: author
  orcid: https://orcid.org/0000-0002-9451-8147
  organization: National Institute for Materials Science

## Contact agent



## Publisher

organization: Informa UK Limited

## Managing organization



## Keyword

- subject: Hydroxyapatite/collagen nanocomposite
  schema: not_defined
- subject: "(3-glycidoxypropyl) trimethoxysilane"
  schema: not_defined
- subject: bone paste
  schema: not_defined
- subject: mechanical properties
  schema: not_defined
- subject: biocompatibility
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Journal of Asian Ceramic Societies
  issn: '21870764'
  volume: '6'
  issue: '4'
  start_page: 322
  end_page: 331

## Conference



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## Instrument



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## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



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## Fileset

- id: 15762ebd-59f3-4049-8f89-34987eabad70
  filename: Preparation of anti decay self setting pastes of hydroxyapatite collagen
    utilizing 3 glycidoxypropyl trimethoxysilane.pdf
  content_type: application/pdf
  size: 1963144
  md5: '09f990682dfddf11aab76e6a0ff749ea'

## Thumbnail

fileset_id: 15762ebd-59f3-4049-8f89-34987eabad70
filename: Preparation of anti decay self setting pastes of hydroxyapatite collagen
  utilizing 3 glycidoxypropyl trimethoxysilane.pdf