# Sprayable gelatin microparticles prevent delayed gastric bleeding in an anticoagulated swine model

https://mdr.nims.go.jp/datasets/399246a3-5d2e-4b39-91e7-c0967ea07886

## File

- [R3_hMPs_Bleeding_MANUSCRIPIT_20260128_Clean.pdf](https://mdr.nims.go.jp/filesets/650d455d-e413-44c5-949a-356f321d2746/download) ([Detail](https://mdr.nims.go.jp/filesets/650d455d-e413-44c5-949a-356f321d2746.md))

## Id

399246a3-5d2e-4b39-91e7-c0967ea07886

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2026-03-13T02:03:06.939443Z

## Updated at

2026-03-16T00:03:32.468350Z

## Published at

2026-03-16T08:54:54.606822Z

## Doi

https://doi.org/10.48505/nims.6218

## First published url

https://doi.org/10.1038/s41598-026-38423-9

## Date published

2026-02-03

## Recorded date published



## Resource type

journal_article

## Manuscript type

accepted_manuscript

## Collection



## Title

- title: Sprayable gelatin microparticles prevent delayed gastric bleeding in an anticoagulated
    swine model
  title_type: original
  lang: en

## Description

- description: Delayed bleeding following endoscopic mucosal resection or endoscopic
    submucosal dissection is a serious concern in patients receiving anticoagulant
    therapy. We previously established an experimental animal model of delayed gastric
    bleeding following endoscopic resection under controlled anticoagulation. In this
    study, we aimed to evaluate the potential preventive effect of hydrophobized microparticles
    (hMPs), a novel sprayable wound-covering material derived from Alaska pollock
    gelatin, in preventing delayed bleeding.
  description_type: abstract
  lang: und

## Creator

- name: Shohei Uehara
  role: author
- name: Fumisato Sasaki
  role: author
- name: Hidehito Maeda
  role: author
- name: Makoto Hinokuchi
  role: author
- name: Akihito Tanaka
  role: author
- name: Shiho Arima
  role: author
- name: Shinichi Hashimoto
  role: author
- name: Shuji Kanmura
  role: author
- name: Hisashi Sahara
  role: author
- name: Yasuko Kobayashi
  role: author
- name: Akihiro Nishiguchi
  role: author
  orcid: https://orcid.org/0000-0002-3160-6385
  organization: National Institute for Materials Science
- name: Tetsushi Taguchi
  role: author
  orcid: https://orcid.org/0000-0003-2541-2530
  organization: National Institute for Materials Science

## Contact agent



## Publisher

organization: Springer Science and Business Media LLC

## Managing organization



## Keyword

- subject: Endoscopic submucosal dissection
  schema: not_defined
- subject: Endoscopic mucosal resection
  schema: not_defined
- subject: Delayed gastric bleeding
  schema: not_defined
- subject: Anticoagulation therapy
  schema: not_defined
- subject: Hydrophobized microparticlesl
  schema: not_defined
- subject: animal mode
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Scientific Reports
  issn: '20452322'
  volume: '16'
  issue: '1'
  article_number: '7075'

## Conference



## Related item



## Funding

- funder_name: Japan Society for the Promotion of Science KAKENHI
- funder_name: Japan Agency of Medical Research and Development

## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 650d455d-e413-44c5-949a-356f321d2746
  filename: R3_hMPs_Bleeding_MANUSCRIPIT_20260128_Clean.pdf
  content_type: application/pdf
  size: 433117
  md5: bd09e84418aa268217063cc0e6831d50

## Thumbnail

fileset_id: 650d455d-e413-44c5-949a-356f321d2746
filename: R3_hMPs_Bleeding_MANUSCRIPIT_20260128_Clean.pdf