# Tailored portable electrochemical sensor for dopamine detection in human fluids using heteroatom-doped three-dimensional g-C3N4 hornet nest structure

https://mdr.nims.go.jp/datasets/2b353dd9-df32-49d4-a6bb-4f48edfd61ff

## File

- [Manuscript -F- V2-Clean.docx](https://mdr.nims.go.jp/filesets/27cf8331-cd4e-4b14-af45-6ca1aa0a7abc/download) ([Detail](https://mdr.nims.go.jp/filesets/27cf8331-cd4e-4b14-af45-6ca1aa0a7abc.md))

## Id

2b353dd9-df32-49d4-a6bb-4f48edfd61ff

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-12-16T08:56:03.111197Z

## Updated at

2025-12-22T04:04:34.000028Z

## Published at

2025-12-22T07:22:04.934308Z

## Doi

https://doi.org/10.48505/nims.6048

## First published url

https://doi.org/10.1016/j.aca.2024.342985

## Date published

2024-07-17

## Recorded date published

2024-9

## Resource type

journal_article

## Manuscript type

authors_original

## Collection



## Title

- title: Tailored portable electrochemical sensor for dopamine detection in human
    fluids using heteroatom-doped three-dimensional g-C3N4 hornet nest structure
  title_type: original
  lang: en

## Description

- description: This paper describes the development of a portable electrochemical
    sensor for the sensitive and selective detection of dopamine, a clinically important
    neurotransmitter associated with neurodegenerative diseases such as Parkinson’s
    and Alzheimer’s. The sensor is based on a three-dimensional phosphorus- and sulfur-doped
    graphitic carbon nitride hornet’s nest structure, which features a hierarchical
    porous morphology with multi-open hexagonal gates, abundant voids, and a rough,
    wave-oriented surface that collectively provide a high surface area and facilitate
    efficient electrolyte diffusion and dopamine adsorption. Phosphorus and sulfur
    doping introduces phosphate and sulfate functionalities that enhance charge transfer,
    improve dopamine binding, and impart high selectivity. When integrated onto a
    screen-printed carbon electrode, the sensor exhibits a low detection limit of
    7.8 nM and a wide linear range from 10 to 500 nM. The platform demonstrates excellent
    stability, reproducibility, and high recovery of dopamine in human serum and urine
    samples, highlighting its strong potential for practical clinical and point-of-care
    applications.
  description_type: abstract
  lang: en

## Creator

- name: Mohammed Y. Emran
  role: author
  orcid: https://orcid.org/0000-0002-0605-7118
  organization: National Institute for Materials Science
- name: Ahmed Kotb
  role: author
- name: Akhilesh Babu Ganganboina
  role: author
  orcid: https://orcid.org/0000-0003-3259-5080
  organization: National Institute for Materials Science
- name: Akihiro Okamoto
  role: author
  orcid: https://orcid.org/0000-0002-8102-4316
  organization: National Institute for Materials Science
- name: Tariq Z. Abolibda
  role: author
- name: Hassan A.H. Alzahrani
  role: author
- name: Sobhi M. Gomha
  role: author
- name: Chongbo Ma
  role: author
- name: Ming Zhou
  role: author
- name: Mohamed A. Shenashen
  role: author

## Contact agent



## Publisher

organization: Elsevier BV

## Managing organization



## Keyword

- subject: Porous g-C3N4; Multifunctional surface interface; Portable electrochemical
    sensor; Dopamine; Neuronal diseases; Biological samples
  schema: not_defined

## Rights

- identifier: http://rightsstatements.org/vocab/InC/1.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: Analytica Chimica Acta
  issn: '00032670'
  volume: '1320'
  article_number: '342985'

## Conference



## Related item



## Funding



## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



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## Custom property



## Fileset

- id: 27cf8331-cd4e-4b14-af45-6ca1aa0a7abc
  filename: Manuscript -F- V2-Clean.docx
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  size: 2956823
  md5: d283773cb4f67996b4809c0b59cabf31

## Thumbnail

fileset_id: 27cf8331-cd4e-4b14-af45-6ca1aa0a7abc
filename: Manuscript -F- V2-Clean.docx