# Boron nitride nanomaterials for cancer therapy: tailor-made strategies

https://mdr.nims.go.jp/datasets/2abe4f57-936f-45d3-9bf2-bb7aa23ec648

## File

- [2025 JMR -Xia Li.pdf](https://mdr.nims.go.jp/filesets/a97a0a22-18c7-4996-bd6a-8342d1d0e91c/download) ([Detail](https://mdr.nims.go.jp/filesets/a97a0a22-18c7-4996-bd6a-8342d1d0e91c.md))

## Id

2abe4f57-936f-45d3-9bf2-bb7aa23ec648

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2025-12-08T04:53:19.941082Z

## Updated at

2025-12-09T07:30:52.781322Z

## Published at

2025-12-09T07:26:05.090814Z

## Doi



## First published url

https://doi.org/10.1557/s43578-025-01633-4

## Date published

2025-07-28

## Recorded date published

2025-7-28

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: 'Boron nitride nanomaterials for cancer therapy: tailor-made strategies'
  title_type: original
  lang: en

## Description

- description: Boron nitride (BN) nanomaterials are an emerging biomaterial with great
    potential for cancer treatment owing to their excellent biocompatibility, light
    weight, high chemotherapeutic drug loading capacity (> 300 wt%), stimuli - responsive
    release behavior (such as pH and neutron irradiation), and unique biological activity.
    The objective of this review is to provide a comprehensive overview of the latest
    advancements in the field of tailoring BN nanomaterials for cancer therapy. The
    review will establish the design principles of BN nanomaterials that are suitable
    for cancer treatment. It will summarize the synthesis methods, the ways to improve
    their dispersibility in aqueous solution, and the biocompatibility and the biodegradability
    of BN nanomaterials. Furthermore, a comprehensive review of the application of
    BN nanomaterials in cancer therapy will be presented, encompassing the delivery
    of chemotherapy drug, their intrinsic anticancer effects, boron neutron capture
    therapy, cancer immunotherapy, irreversible electroporation and combination therapy.
    BN nanomaterials with tunable sizes ranging from a few to hundreds of nanometers
    show great promise in the treatment of various cancers, such as prostate cancer,
    breast cancer, glioblastoma, and so on. Finally, we will present prospects regarding
    future directions in this evolving field of tailoring BN nanomaterials to reshape
    cancer therapy.
  description_type: abstract
  lang: eng

## Creator

- name: Xia Li
  role: author
  orcid: https://orcid.org/0000-0002-3246-4462
  organization: National Institute for Materials Science
  department: Research Center for Macromolecules and Biomaterials/Biomaterials Field/Smart
    Polymers Group
- name: Nobutaka Hanagata
  role: author
  orcid: https://orcid.org/0000-0001-6079-3426
  organization: National Institute for Materials Science
- name: Dmitri Golberg
  role: author
  orcid: https://orcid.org/0000-0003-2298-6539
  organization: National Institute for Materials Science
  department: Research Center for Materials Nanoarchitectonics (MANA)

## Contact agent



## Publisher

organization: Springer Nature

## Managing organization



## Keyword

- subject: boron nitride nanomaterials
  schema: not_defined
- subject: cancer therapy
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin

- data_origin_type: other

## Embargo



## Journal

- title: JOURNAL OF MATERIALS RESEARCH
  issn: '20445326'
  volume: '40'
  issue: '14'

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## Specimen



## Chemical composition



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## Fileset

- id: a97a0a22-18c7-4996-bd6a-8342d1d0e91c
  filename: 2025 JMR -Xia Li.pdf
  content_type: application/pdf
  size: 7425612
  md5: ff18a33c98ad1886104fea665f48068e

## Thumbnail

fileset_id: a97a0a22-18c7-4996-bd6a-8342d1d0e91c
filename: 2025 JMR -Xia Li.pdf