# Two-dimensional nanomaterials based on rare earth elements for biomedical applications

https://mdr.nims.go.jp/datasets/28f34a75-656d-4b3d-a85b-dff553f08588

## File

- [Bai_D4SC02625J.pdf](https://mdr.nims.go.jp/filesets/fa3a2d38-6589-4a78-bb63-903ce06a38d9/download) ([Detail](https://mdr.nims.go.jp/filesets/fa3a2d38-6589-4a78-bb63-903ce06a38d9.md))

## Id

28f34a75-656d-4b3d-a85b-dff553f08588

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2024-10-24T05:00:14.085995Z

## Updated at

2024-10-25T07:30:33.372980Z

## Published at

2024-10-25T07:30:33.584655Z

## Doi



## First published url

https://doi.org/10.1039/d4sc02625j

## Date published

2024-09-19

## Recorded date published

2024-10-23

## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Two-dimensional nanomaterials based on rare earth elements for biomedical
    applications
  title_type: original
  lang: en

## Description

- description: As a kind of star materials, two-dimensional (2D) nanomaterials have
    attracted tremendous attention for their unique structures, excellent performance
    and wide applications. In recent years, layered rare earth-based or doped nanomaterials
    have become a new important member of the 2D nanomaterials family and have attracted
    significant interest, especially the layered rare earth hydroxides (LREHs) and
    layered rare earth-doped perovskites with anion-exchangeability and exfoliative
    properties. In this review, we systematically summarize the synthesis, exfoliation,
    fabrication and biomedical applications of the 2D rare earth nanomaterials. Upon
    exfoliation, the LREHs and layered rare earth-doped perovskites can be dimensionally
    reduced to ultrathin nanosheets which feature high anisotropy and flexibility.
    Subsequent fabrication, especially superlattice assembly, enables rare earth nanomaterials
    with diverse compositions and structures, which further optimizes or even creates
    new properties and thus expands the application fields. The latest progress in
    biomedical applications of the 2D rare earth-based or doped nanomaterials and
    composites are also reviewed in detail, especially drug delivery and magnetic
    resonance imaging (MRI). Moreover, at the end of this review, we provide an outlook
    on the opportunities and challenges of the 2D rare earth-based or doped nanomaterials.
    We believe this review will promote increasing interest in 2D rare earth materials
    and provide more insight into the artificial design of other nanomaterials based
    on rare earth elements for functional applications.
  description_type: abstract
  lang: und

## Creator

- name: Mingjun Bai
  role: author
  orcid: https://orcid.org/0000-0002-9400-6045
- name: Hao Wan
  role: author
  orcid: https://orcid.org/0000-0002-4487-3538
- name: Ying Zhang
  role: author
- name: Siqi Chen
  role: author
- name: Chunyin Lu
  role: author
- name: Xiaohe Liu
  role: author
  orcid: https://orcid.org/0000-0003-1297-9597
- name: Gen Chen
  role: author
- name: Ning Zhang
  role: author
  orcid: https://orcid.org/0000-0002-3033-0276
- name: Renzhi Ma
  role: author
  orcid: https://orcid.org/0000-0001-7126-2006

## Contact agent



## Publisher

organization: Royal Society of Chemistry (RSC)

## Managing organization



## Keyword

- subject: Two-dimensional (2D) nanomaterials
  schema: not_defined
- subject: Rare earth
  schema: not_defined
- subject: Drug delivery
  schema: not_defined
- subject: Magnetic resonance imaging (MRI)
  schema: not_defined

## Rights

- identifier: cc-by-3.0

## Other identifier(s)



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## Embargo



## Journal

- title: Chemical Science
  issn: '20416520'
  volume: '15'
  issue: '41'
  start_page: 16887
  end_page: 16907

## Conference



## Related item



## Funding

- identifier: 22H01916
  funder_name: Japan Society for the Promotion of Science
- identifier: 22K18956
  funder_name: Japan Society for the Promotion of Science
- identifier: U20A20123
  funder_name: National Natural Science Foundation of China
- identifier: KJQN202301134
  funder_name: Chongqing Municipal Education Commission
- identifier: KJQN202301133
  funder_name: Chongqing Municipal Education Commission

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## Fileset

- id: fa3a2d38-6589-4a78-bb63-903ce06a38d9
  filename: Bai_D4SC02625J.pdf
  content_type: application/pdf
  size: 2486049
  md5: 172e8ec428390cae78b14177e954e1ae

## Thumbnail

fileset_id: fa3a2d38-6589-4a78-bb63-903ce06a38d9
filename: Bai_D4SC02625J.pdf