# Detection of Trace Amounts of Water in Organic Solvents by DNA-Based Nanomechanical Sensors

https://mdr.nims.go.jp/datasets/27d0e5e7-7926-402e-ade4-4c784a83cb15

## File

- [biosensors-12-01103.pdf](https://mdr.nims.go.jp/filesets/7b2fd5e5-4603-42ee-8a33-abc779c8f963/download) ([Detail](https://mdr.nims.go.jp/filesets/7b2fd5e5-4603-42ee-8a33-abc779c8f963.md))

## Id

27d0e5e7-7926-402e-ade4-4c784a83cb15

## Local identifier



## Visibility

open_to_public

## State

published

## Created at

2023-07-21T05:25:06.914775Z

## Updated at

2024-01-05T13:11:42.237419Z

## Published at

2023-07-25T04:55:14.581593Z

## Doi



## First published url

https://doi.org/10.3390/bios12121103

## Date published

2022-12-01

## Recorded date published



## Resource type

journal_article

## Manuscript type

vor

## Collection



## Title

- title: Detection of Trace Amounts of Water in Organic Solvents by DNA-Based Nanomechanical
    Sensors
  title_type: original
  lang: en

## Description

- description: Detection of trace amounts of water in organic solvents is of great
    importance in the field of chemistry and industry. Karl-Fischer titration is known
    as a classic method and is widely used for detecting trace amounts of water, however,
    there are some limitations in terms of rapid and direct detection because of its
    time-consuming sample preparation and specific equipment. Here, we found that
    a DNA-based nanomechanical sensor exhibits high sensitivity and selectivity to
    water vapor, leading to the detection and quantification of trace amounts of water
    in organic solvents as low as 12 ppm in THF with ppb-level of LoD through their
    vapor. Since the present method is a simple and rapid method, this approach can
    be an alternative method of the conven-tional Karl-Fischer titration.
  description_type: abstract
  lang: eng

## Creator

- name: Tomohiro Murata
  role: author
- name: Kosuke Minami
  role: author
  orcid: https://orcid.org/0000-0003-4145-1118
  organization: National Institute for Materials Science
  ror: https://ror.org/026v1ze26
- name: Tomohiko Yamazaki
  role: author
  orcid: https://orcid.org/0000-0003-2136-8042
  organization: National Institute for Materials Science
  ror: https://ror.org/026v1ze26
- name: Genki Yoshikawa
  role: author
  orcid: https://orcid.org/0000-0002-9136-8964
  organization: National Institute for Materials Science
  ror: https://ror.org/026v1ze26
- name: Katsuhiko Ariga
  role: author
  orcid: https://orcid.org/0000-0002-2445-2955
  organization: National Institute for Materials Science
  ror: https://ror.org/026v1ze26

## Contact agent



## Publisher

organization: MDPI AG

## Managing organization



## Keyword

- subject: nanomechanical sensors
  schema: not_defined
- subject: Trace amounts of water
  schema: not_defined

## Rights

- identifier: https://creativecommons.org/licenses/by/4.0/

## Other identifier(s)



## Data origin



## Embargo



## Journal

- title: Biosensors-Basel
  issn: '20796374'
  volume: '12'
  issue: '12'
  start_page: 1103
  end_page: 1103

## Conference



## Related item



## Funding



## Instrument



## Instrument operator



## Instrument managing organization



## Measurement method



## Specimen



## Chemical composition



## Structure for specimen



## Structural feature for specimen



## Specific property for specimen



## Process for specimen treatment



## Computational method



## Energy level/transition state



## Software



## Custom property



## Fileset

- id: 7b2fd5e5-4603-42ee-8a33-abc779c8f963
  filename: biosensors-12-01103.pdf
  content_type: application/pdf
  size: 1713025
  md5: b5184457d8f6313c408f06f642b135f4

## Thumbnail

fileset_id: 7b2fd5e5-4603-42ee-8a33-abc779c8f963
filename: biosensors-12-01103.pdf